For professionals in the pharmaceutical and chemical industries, the reliable sourcing of high-quality intermediates is paramount to successful research and development. Among these crucial compounds are boronic acid derivatives, particularly pyrazole boronic esters, which serve as indispensable building blocks in modern organic synthesis. Specifically, 1-(1-Ethoxyethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester (CAS: 1029716-44-6) has garnered significant attention due to its application in synthesizing important pharmaceuticals like Baricitinib. This article aims to guide R&D procurement specialists on how to best source this vital intermediate.

Understanding the Importance of Purity and Specifications

When you buy intermediates, especially those destined for pharmaceutical applications, purity is non-negotiable. Our 1-(1-Ethoxyethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester is consistently supplied at a high purity of 99% min, confirmed by rigorous quality control measures. This ensures that your synthetic pathways are not compromised by impurities, leading to predictable and reproducible results. Understanding the molecular formula (C13H23BN2O3) and molecular weight (266.14) is also key for accurate stoichiometric calculations in your laboratory work.

Applications in Pharmaceutical Synthesis and Drug Discovery

The primary utility of 1-(1-Ethoxyethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester lies in its role as a key intermediate in the synthesis of Baricitinib, a Janus kinase (JAK) inhibitor used in treating certain autoimmune diseases. Beyond this specific application, its structure, featuring a pyrazole ring and a boronic ester group, makes it a versatile reagent in Suzuki-Miyaura cross-coupling reactions and other C-C bond-forming transformations. This versatility makes it an attractive compound for drug discovery research, allowing scientists to explore novel molecular architectures and potential therapeutic agents. As a pharmaceutical intermediate supplier, we cater to both small-scale research needs and larger-scale manufacturing demands.

Navigating the Market: Finding a Reliable Manufacturer in China

When sourcing specialized chemical compounds, identifying a dependable manufacturer is crucial. China has emerged as a global hub for chemical manufacturing, offering competitive pricing and extensive production capacities. For intermediates like 1-(1-Ethoxyethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester, working with established Chinese suppliers ensures not only cost-effectiveness but also access to significant production volumes. Look for suppliers who provide comprehensive documentation, such as Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), and who have a proven track record in supplying to international markets. By partnering with a reputable manufacturer, you can secure a consistent supply chain and gain a competitive edge in your R&D efforts. To purchase this essential intermediate, consider reaching out to experienced providers who understand your quality requirements.