For procurement managers in the pharmaceutical sector, identifying reliable suppliers for critical intermediates like 4-Hydroxypyrrolo[2,3-d]pyrimidine (CAS 3680-71-5) is paramount. This compound, also known as 7-Deazahypoxanthine, serves as a vital building block in the synthesis of various active pharmaceutical ingredients (APIs), most notably in the development of JAK inhibitors like Ruxolitinib Phosphate. Understanding the market and key sourcing strategies will ensure you secure high-purity materials at competitive prices.

When looking to buy 4-Hydroxypyrrolo[2,3-d]pyrimidine, several factors should be considered. Purity is non-negotiable, especially for research and development (R&D) and commercial manufacturing. Reputable suppliers will readily provide Certificates of Analysis (CoA) detailing assay percentages, impurity profiles, and physicochemical properties. Common specifications include a minimum purity of 98-99%, with specific attention paid to single impurity levels.

The CAS number, 3680-71-5, is the universal identifier for this chemical. When searching for a supplier, utilizing this CAS number along with terms like 'pharmaceutical intermediate,' 'buy,' and 'China' will yield relevant results. Many Chinese manufacturers specialize in producing these complex organic molecules, offering cost advantages and large-scale production capabilities. For instance, locating a trusted manufacturer in Jiangsu or Shandong province can be a strategic move.

Beyond purity, consider the supplier's overall reliability. This includes their production capacity, adherence to quality management systems (such as ISO 9001 or GMP certifications where applicable), and their ability to provide consistent batches. Factors like lead times, shipping options, and customer support are also crucial. Engaging with a supplier early in your project can help ensure a smooth procurement process.

Moreover, don't hesitate to request samples. Testing a small quantity of 4-Hydroxypyrrolo[2,3-d]pyrimidine from a potential supplier allows you to verify its quality and suitability for your specific application before committing to larger orders. Competitive pricing is always a consideration, but it should never come at the expense of quality or supply chain security.

For businesses seeking to purchase C6H5N3O or other Pyrrolo[2,3-d]pyrimidine derivatives, leveraging online chemical marketplaces and direct supplier inquiries is effective. Platforms like Made-in-China.com or specialized chemical sourcing websites can connect you with numerous manufacturers. Remember to thoroughly vet potential partners. By focusing on quality, reliability, and competitive pricing, you can secure the essential intermediates needed for your pharmaceutical innovations.