In the dynamic world of pharmaceutical development and advanced chemical research, access to specialized raw materials is critical. For procurement specialists and R&D scientists, identifying and securing high-quality, specific chemical entities can be a significant undertaking. Among these specialized materials, unnatural amino acids and their derivatives play an increasingly vital role. This guide focuses on Boc-D-2,3,4,5,6-pentafluorophenylalanine (CAS 136207-26-6), detailing its importance and how to effectively source it.

Boc-D-2,3,4,5,6-pentafluorophenylalanine is a protected D-amino acid featuring a pentafluorinated phenyl ring. This unique structure makes it an invaluable building block in several key areas:

  • Peptide Synthesis: The incorporation of unnatural amino acids like this one allows for the creation of peptides with modified properties. The D-configuration often confers increased resistance to enzymatic degradation, while the pentafluorophenyl group can influence binding affinity, lipophilicity, and metabolic stability.
  • Drug Discovery: As a pharmaceutical intermediate, it serves as a crucial component in the synthesis of novel drug candidates. Its presence can enhance the pharmacological profile of small molecules or peptide-based therapeutics.
  • Organic Synthesis: Researchers in organic chemistry utilize such compounds to explore new reaction pathways and construct complex molecular architectures.

When considering the purchase of Boc-D-2,3,4,5,6-pentafluorophenylalanine, several factors are paramount for B2B buyers:

1. Purity: For pharmaceutical and sensitive research applications, high purity is non-negotiable. A minimum purity of 97% is generally the standard, ensuring that the material is free from significant impurities that could interfere with synthesis or lead to erroneous experimental results. Always review the Certificate of Analysis (CoA) to confirm specifications.

2. Chemical Specifications: Confirm that the product is indeed the D-isomer and that it features the Boc protecting group, as these are critical for its intended applications in controlled synthesis.

3. Reliable Supply Chain & Manufacturing: Identifying a reputable manufacturer and supplier is crucial. For cost-effectiveness and consistent availability, sourcing from manufacturers in China specializing in fine chemicals and pharmaceutical intermediates is a common and often advantageous practice. Look for suppliers with established quality control systems and a track record of reliability.

4. Pricing and Quotation: Obtain quotes from multiple suppliers to ensure competitive pricing. Understanding the pricing structure, especially for bulk purchases, is essential for budgeting research and production costs.

We, as a dedicated manufacturer and supplier of chemical intermediates, offer Boc-D-2,3,4,5,6-pentafluorophenylalanine with a guaranteed purity of ≥97%. We are committed to supporting the R&D efforts of pharmaceutical companies and research institutions by providing high-quality materials at competitive prices. Our aim is to be a dependable partner, ensuring that you can buy this essential building block with confidence.

In conclusion, sourcing specialty amino acids like Boc-D-2,3,4,5,6-pentafluorophenylalanine requires a meticulous approach. By focusing on purity, accurate specifications, and the reliability of your supplier, you can secure the high-quality intermediates needed to drive your scientific and commercial objectives forward.