For procurement professionals and R&D scientists in the chemical and pharmaceutical sectors, the strategic sourcing of essential intermediates is a cornerstone of efficient project execution. 1-Boc-4-piperidinecarboxaldehyde (CAS 137076-22-3) is a versatile and vital compound, indispensable for a wide range of synthetic applications. This buyer's guide aims to equip you with the knowledge to effectively procure this intermediate, emphasizing quality, cost-effectiveness, and supplier reliability, especially when sourcing from China.

Understanding the Utility of 1-Boc-4-piperidinecarboxaldehyde

1-Boc-4-piperidinecarboxaldehyde is a protected piperidine derivative with a reactive aldehyde group, making it a key building block in organic synthesis. Its utility extends across numerous pharmaceutical research areas. It is critically important for the synthesis of advanced compounds like Pim-1 inhibitors used in cancer research, selective GPR119 agonists for type II diabetes treatment, and inhibitors targeting HIV-1 replication. The demand for this chemical reflects its broad impact on drug discovery and development.

Key Considerations for Buyers

When initiating the procurement process for 1-Boc-4-piperidinecarboxaldehyde, buyers should prioritize the following:

  • Purity and Quality Assurance: The compound must meet stringent purity specifications, typically 97% or higher, with a comprehensive Certificate of Analysis (CoA) provided by the supplier.
  • Supplier Reputation and Capability: Thoroughly vet potential suppliers for their manufacturing capabilities, track record, and customer service. Established manufacturers with robust quality control systems are preferable.
  • Cost-Effectiveness and Transparent Pricing: While cost is a significant factor, it should not overshadow quality and reliability. Obtain detailed quotes that include all associated costs, such as shipping and handling.
  • Supply Chain Stability: Ensure the supplier can provide a consistent and scalable supply to meet your project's needs, from initial research quantities to commercial production.

Navigating the Chinese Market for 1-Boc-4-piperidinecarboxaldehyde

China is a primary global source for fine chemicals, and many reputable manufacturers offer 1-Boc-4-piperidinecarboxaldehyde. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are recognized for their commitment to quality and competitive pricing. To ensure a successful transaction when buying from China:

  • Verify Credentials: Look for suppliers with ISO certifications and positive reviews, indicating a commitment to quality and customer satisfaction.
  • Request Samples: Always test samples to confirm product quality and suitability before committing to larger orders.
  • Clear Communication and Logistics: Establish clear communication channels and confirm shipping details, Incoterms, and payment terms to ensure a smooth transaction.

Conclusion

Effectively sourcing 1-Boc-4-piperidinecarboxaldehyde (CAS 137076-22-3) is crucial for advancing pharmaceutical research and development. By focusing on quality, supplier reliability, and cost-effectiveness, and by partnering with manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., you can secure a vital intermediate that drives innovation. Contact us to discuss your procurement needs and discover how our expertise can benefit your organization.