In the complex world of chemical procurement, obtaining high-quality intermediates like 5,6,7,8-Tetrahydro-2-naphthol (CAS 1125-78-6) is critical for the success of R&D projects and large-scale manufacturing. This guide is designed for purchasing managers, R&D scientists, and formulators seeking to secure a reliable supply of this important compound. We will cover key aspects of sourcing, from identifying reputable suppliers to understanding pricing and quality assurances.

Understanding the Product: 5,6,7,8-Tetrahydro-2-naphthol

5,6,7,8-Tetrahydro-2-naphthol, also known by its CAS number 1125-78-6, is a white crystalline solid with a melting point of 59-61°C. Its primary significance lies in its use as a pharmaceutical intermediate, most notably in the synthesis of Liranaftate. The typical assay provided by manufacturers is ≥98.0%, a standard for many chemical applications. Its consistent properties and availability are key factors for its widespread use.

Identifying Potential Suppliers and Manufacturers

When you need to buy 5,6,7,8-Tetrahydro-2-naphthol, the first step is to identify potential manufacturers and suppliers. The global market offers numerous options, but focusing on those with a strong track record and transparent practices is advisable. Key indicators of a reliable supplier include:

  • Direct Manufacturer Status: Sourcing directly from the manufacturer eliminates layers of distribution, often leading to better prices and direct quality control.
  • Product Specificity: Suppliers who prominently list CAS 1125-78-6 with detailed specifications (purity, appearance, molecular weight) are more likely to be knowledgeable and reliable.
  • Geographic Concentration: China is a major hub for chemical manufacturing, offering competitive pricing and a vast supplier network. Terms like 'manufacturer in China' are therefore highly relevant.
  • Online Presence and Reviews: A professional website, clear contact information, and positive reviews or testimonials can indicate a trustworthy supplier.

Requesting Quotes and Negotiating Price

Once you have identified potential suppliers, the next step is to request quotes. When you contact a supplier to inquire about the price of 5,6,7,8-Tetrahydro-2-naphthol, be prepared to provide detailed information about your requirements:

  • Quantity: Specify the amount you need (e.g., kilograms, tons). The price per unit typically decreases with larger order volumes.
  • Purity Requirements: While ≥98.0% is standard, confirm if any specific impurity limits are critical for your application.
  • Packaging: Standard packaging is often 25 kg/drum, but custom packaging options may be available.
  • Delivery Timeline: Clearly state your required delivery date and destination.

Comparing quotes from multiple suppliers will help you secure the best possible price for this vital intermediate.

Ensuring Quality and Reliability

Beyond price, quality and reliability are paramount, especially for pharmaceutical applications. Always request a Certificate of Analysis (COA) with each batch to verify purity and specifications. A reputable supplier will also offer support regarding safety data sheets (SDS) and regulatory compliance. Building a long-term relationship with a trusted supplier can ensure continuity of supply and preferential treatment for future orders.

In conclusion, the strategic sourcing of 5,6,7,8-Tetrahydro-2-naphthol (CAS 1125-78-6) involves careful supplier selection, thorough negotiation, and a commitment to quality assurance. By leveraging the resources of global manufacturers, particularly in China, buyers can confidently procure this essential intermediate for their critical projects.