For professionals in the chemical and pharmaceutical industries, securing a consistent and high-quality supply of essential intermediates is paramount. Tert-Butyl 5-Bromopentanoate (CAS 88987-42-2) stands out as a versatile and critical building block for a wide array of synthetic applications, from pharmaceutical research to the development of agrochemicals and specialized reagents. As a procurement manager, understanding where to source this compound efficiently and cost-effectively is key to project success.

Understanding Tert-Butyl 5-Bromopentanoate

Tert-Butyl 5-Bromopentanoate, also known by synonyms such as tert-butyl 5-bromovalerate or 5-BROMOPENTANOIC ACID, T-BUTYL ESTER, is characterized by its liquid form, typically appearing as a colorless to light yellow substance. Its molecular formula is C9H17BrO2, with a molecular weight of approximately 237.13 g/mol. The compound is particularly valued for its role in organic synthesis, notably in the preparation of haptens used for the production of monoclonal antibodies. Researchers often utilize it in multi-step synthetic pathways where the tert-butyl ester and bromoalkyl functionalities are strategically employed.

Key Applications in Research and Industry

The utility of Tert-Butyl 5-Bromopentanoate spans several high-value sectors:

  • Pharmaceutical Intermediates: It serves as a precursor for synthesizing various pharmaceutical compounds and drug candidates. Its structure allows for further functionalization, making it a valuable starting material in medicinal chemistry.
  • Agrochemical Synthesis: The compound is also employed in the creation of new agrochemicals, contributing to the development of more effective crop protection agents.
  • Monoclonal Antibody Production: As highlighted in several studies, it's a crucial reactant in synthesizing haptens, which are essential for generating highly specific antibodies used in diagnostic assays like ELISA.
  • General Organic Synthesis: Its reactive bromide group and protected carboxylic acid moiety make it a versatile reagent for various carbon-carbon bond-forming reactions and other synthetic transformations.

Sourcing Strategies for Procurement Managers

When looking to buy Tert-Butyl 5-Bromopentanoate, procurement managers should focus on suppliers that offer high purity (often 99% or more) and reliable delivery. China has emerged as a major hub for chemical manufacturing, offering competitive pricing, especially for bulk purchases. When evaluating potential suppliers, consider the following:

  • Manufacturer vs. Distributor: Direct sourcing from manufacturers often yields better pricing and more consistent quality control. Look for audited suppliers with a proven track record.
  • Purity and Specifications: Always verify that the product meets your specific purity requirements and analytical standards. Requesting Certificates of Analysis (CoA) is standard practice.
  • Supplier Reputation: Online platforms like Alibaba.com and Made-in-China.com provide ratings and reviews that can help assess supplier reliability.
  • Customization and Sample Availability: For specific project needs, inquire about custom synthesis or the availability of samples for testing.
  • Pricing and Lead Times: Obtain quotes from multiple suppliers to compare prices and delivery schedules. Factor in shipping costs and customs procedures.

Finding Reliable Suppliers in China

Many reputable chemical manufacturers based in China specialize in producing fine chemical intermediates like Tert-Butyl 5-Bromopentanoate. Companies often list their products with CAS numbers, purity levels, and application details. For instance, searching for 'tert-butyl 5-bromopentanoate manufacturer China' or 'CAS 88987-42-2 supplier' can yield numerous results. When you identify potential suppliers, engaging them through their official contact channels or via sourcing platforms to request a quote is the next logical step. This allows for direct communication regarding quantity, pricing, and any specific quality assurances needed.

In conclusion, by understanding the product's properties and applications and employing a strategic sourcing approach, procurement managers can efficiently secure Tert-Butyl 5-Bromopentanoate (CAS 88987-42-2) from trusted Chinese manufacturers, ensuring the smooth progression of their critical research and production initiatives.