In the dynamic landscape of chemical synthesis, the availability of reliable and high-quality intermediates is paramount. tert-Butyl N-(4-hydroxybutyl)carbamate, commonly known as 4-(Boc-amino)-1-butanol and bearing the CAS number 75178-87-9, is a compound of significant interest due to its versatile applications in pharmaceutical development, polymer science, and organic synthesis. This guide aims to assist procurement professionals and researchers in effectively sourcing this crucial chemical, highlighting its properties and the importance of choosing the right supplier.

Understanding the Chemical Properties and Advantages

tert-Butyl N-(4-hydroxybutyl)carbamate is characterized by its unique molecular structure, featuring a Boc (tert-butoxycarbonyl) protecting group on an amine and a primary alcohol group. This dual functionality is the key to its broad utility. The Boc group provides stable protection for the amine moiety, allowing selective reactions at the hydroxyl end. This protection is readily removable under mild acidic conditions, typically with reagents like TFA or HCl, enabling subsequent functionalization of the amine. This control over reactivity makes it an ideal building block for creating complex molecules, a feature that drives many to buy this compound for their sophisticated synthetic routes. Its typical appearance as a colorless to yellow liquid or low melting solid, with purity levels of 98% or higher, ensures its suitability for demanding applications.

Key Applications in Synthesis and Development

The versatility of tert-Butyl N-(4-hydroxybutyl)carbamate makes it indispensable in several areas:

  • Pharmaceutical Intermediates: It serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, contributing to the development of advanced therapeutics.
  • Polymer Synthesis: The compound is utilized in creating polymers for specialized applications, most notably in the synthesis of polymers for in vivo delivery polyconjugate systems, crucial for targeted drug delivery.
  • Organic Synthesis: As a bifunctional building block, it facilitates the construction of complex organic frameworks, supporting advancements in medicinal chemistry and materials science.

For professionals involved in these sectors, securing a consistent supply of this intermediate is vital. Whether you need it for early-stage research or large-scale production, identifying a reliable manufacturer is the first step.

Choosing the Right Supplier: Quality, Price, and Reliability

When you decide to purchase tert-Butyl N-(4-hydroxybutyl)carbamate, several factors should guide your choice of supplier. Prioritize manufacturers that guarantee high purity (e.g., ≥98% or ≥99%) and provide comprehensive documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS). Competitive price is also a key consideration, and working with a prominent manufacturer in China can often provide significant cost advantages while ensuring quality. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing such high-value chemical intermediates, offering both quality assurance and efficient service.

Procurement Best Practices

To ensure a smooth procurement process, clearly define your needs regarding quantity, purity, and packaging. Always confirm the supplier's quality control processes and their ability to meet your delivery timelines. For bulk orders, direct engagement with manufacturers can optimize pricing and supply chain stability. Proper storage, typically at 2-8°C in tightly sealed containers, is also crucial for maintaining the compound's integrity and performance.

In conclusion, tert-Butyl N-(4-hydroxybutyl)carbamate is a foundational intermediate for numerous advanced chemical applications. By strategically selecting your suppliers and focusing on quality and reliability, you can effectively leverage this compound to drive innovation in your research and manufacturing endeavors.