Sourcing Tofacitinib Intermediates: A Guide for Pharmaceutical Manufacturers
For pharmaceutical manufacturers engaged in the production of Tofacitinib Citrate, securing a consistent and high-quality supply of key intermediates is paramount. One such critical component is the compound identified by CAS number 477600-71-8, chemically known as (2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid compd. with (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine (1:2). This article delves into the importance of this intermediate and provides guidance on sourcing it effectively.
The pharmaceutical industry relies heavily on precise chemical synthesis pathways to develop effective treatments. Tofacitinib Citrate, a Janus kinase inhibitor, is used in the treatment of various autoimmune diseases. The synthesis of such complex molecules requires specialized intermediates, and CAS 477600-71-8 plays a pivotal role in its manufacturing process. Its specific stereochemistry and functional groups make it an indispensable building block.
When looking to buy pharmaceutical intermediates, especially for APIs like Tofacitinib Citrate, manufacturers must prioritize purity, reliability, and cost-effectiveness. Sourcing from a reputable Tofacitinib Citrate intermediate supplier in China can offer significant advantages. Chinese manufacturers often provide competitive pricing due to economies of scale and advanced production capabilities, without compromising on quality. It is crucial to partner with suppliers who can demonstrate adherence to international quality standards, such as GMP and ISO certifications, and provide comprehensive product documentation.
The selection of an intermediate supplier should also consider their ability to provide custom synthesis of Tofacitinib intermediate if specific modifications or higher purity grades are required. Understanding the price for (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine and related precursors is also vital for effective cost management in API production. Many suppliers offer detailed technical specifications and analytical data, allowing procurement managers and R&D scientists to make informed decisions.
For businesses seeking to optimize their supply chain for Tofacitinib Citrate production, identifying a dependable manufacturer for CAS 477600-71-8 is a strategic move. By leveraging the expertise of specialized chemical suppliers, pharmaceutical companies can ensure the timely availability of high-quality intermediates, thereby accelerating drug development and ensuring consistent product output. We invite you to inquire about our high-purity pharmaceutical intermediates and discover how we can support your manufacturing needs.
Perspectives & Insights
Logic Thinker AI
“For pharmaceutical manufacturers engaged in the production of Tofacitinib Citrate, securing a consistent and high-quality supply of key intermediates is paramount.”
Molecule Spark 2025
“One such critical component is the compound identified by CAS number 477600-71-8, chemically known as (2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid compd.”
Alpha Pioneer 01
“This article delves into the importance of this intermediate and provides guidance on sourcing it effectively.”