For professionals in the pharmaceutical and chemical industries, sourcing high-quality intermediates is paramount. One such critical compound is 3,4,5-Trimethoxybenzaldehyde, identified by its CAS number 86-81-7. This article aims to guide procurement managers and R&D scientists through the process of acquiring this essential organic intermediate, focusing on reliability, purity, and competitive pricing from reputable China suppliers.

Understanding 3,4,5-Trimethoxybenzaldehyde (CAS 86-81-7)

3,4,5-Trimethoxybenzaldehyde is a white to creamy powder with a molecular formula of C10H12O4 and a molecular weight of 196.2. Its precise chemical structure makes it an indispensable building block in organic synthesis. The compound's melting point typically ranges from 72-74 °C, and it exhibits limited solubility in water but good solubility in organic solvents like methanol and ethanol.

Key Applications in Pharmaceutical Synthesis

The primary and most significant application of 3,4,5-Trimethoxybenzaldehyde lies in its role as a key intermediate for synthesizing antibacterial synergists. Most notably, it is a crucial precursor in the production of Trimethoprim (TMP). Trimethoprim is widely used in combination with sulfonamides to create potent antibacterial agents that are effective against a broad spectrum of bacterial infections. By inhibiting dihydrofolate reductase, Trimethoprim synergizes with sulfonamides to block folic acid synthesis in bacteria, thereby enhancing their therapeutic effect. This makes sourcing high-purity 3,4,5-Trimethoxybenzaldehyde critical for pharmaceutical manufacturers looking to produce effective antimicrobial drugs.

Navigating the Procurement Process: What to Look For

When looking to buy 3,4,5-trimethoxybenzaldehyde online, it's essential to partner with reliable manufacturers and suppliers. Key considerations include:

  • Purity: Aim for a purity of 99% or higher, as specified in the technical data sheets. High purity ensures the efficacy and safety of the final pharmaceutical product and minimizes side reactions during synthesis.
  • CAS Number Verification: Always confirm the CAS number 86-81-7 to ensure you are sourcing the correct compound.
  • Supplier Reputation: Choose manufacturers and suppliers with a proven track record, excellent quality control measures, and positive customer reviews. Look for suppliers who can provide Certificates of Analysis (CoA) and other necessary documentation.
  • Manufacturing Standards: Inquire about the manufacturing processes and compliance with relevant quality standards (e.g., ISO certifications).
  • Pricing: While quality is paramount, competitive pricing is also a factor. Comparing 3,4,5-trimethoxybenzaldehyde price China from multiple verified suppliers can help you secure the best value.

Finding a Reliable 3,4,5-Trimethoxybenzaldehyde Manufacturer

China has emerged as a significant hub for the production of pharmaceutical intermediates. Many Chinese chemical companies specialize in producing compounds like 3,4,5-Trimethoxybenzaldehyde, offering competitive 3,4,5-trimethoxybenzaldehyde manufacturer solutions. When selecting a supplier, prioritize those who demonstrate transparency in their operations and can provide consistent product quality. For instance, seeking a cas 86-81-7 supplier for trimethoprim synthesis who understands the specific requirements of pharmaceutical production is crucial.

The Advantage of Purchasing from Established Suppliers

For procurement managers, the advantage of working with an established 3,4,5-trimethoxybenzaldehyde supplier goes beyond just receiving the product. It encompasses consistent availability, adherence to delivery schedules, and robust technical support. We, as a dedicated manufacturer and supplier, understand the critical nature of this compound and are committed to providing reliable access to high-quality 3,4,5-Trimethoxybenzaldehyde for your pharmaceutical manufacturing needs. We offer transparent pricing and efficient logistics to ensure your supply chain remains uninterrupted.

In conclusion, sourcing 3,4,5-Trimethoxybenzaldehyde (CAS 86-81-7) requires careful consideration of purity, supplier reliability, and application-specific needs. By partnering with experienced manufacturers and suppliers in China, pharmaceutical companies can ensure a stable and cost-effective supply of this vital intermediate, contributing to the production of essential antibacterial medications.