For pharmaceutical manufacturers and formulators, sourcing high-quality active pharmaceutical ingredients (APIs) and their intermediates is paramount. Venlafaxine Hydrochloride (CAS 99300-78-4) is a critical chemical intermediate widely used in the production of antidepressant medications that function as serotonin-norepinephrine reuptake inhibitors (SNRIs). Understanding the nuances of procuring this compound is key to ensuring product efficacy and patient safety. This guide is designed for procurement managers and R&D scientists seeking reliable sources for Venlafaxine Hydrochloride.

Understanding Venlafaxine Hydrochloride's Role

Venlafaxine Hydrochloride is synthesized into medications that treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. Its mechanism of action involves increasing levels of serotonin and norepinephrine in the brain, which are crucial neurotransmitters for mood regulation. As a key intermediate, its purity and consistent quality directly impact the final drug product's effectiveness and safety profile.

Key Quality Parameters to Consider

When looking to buy Venlafaxine Hydrochloride, prioritize suppliers who can consistently deliver a product with a minimum purity of 99.00%. Other critical specifications include its molecular formula (C17H28ClNO2) and molecular weight (313.86). Reliable manufacturers will provide Certificates of Analysis (CoA) detailing these parameters, along with batch-specific testing results for impurities and moisture content (≤0.1% for water is typical). These documents are indispensable for quality control and regulatory compliance.

Finding a Reputable Manufacturer and Supplier in China

China has emerged as a significant hub for pharmaceutical chemical manufacturing. Identifying a trustworthy Venlafaxine Hydrochloride manufacturer involves due diligence. Look for suppliers with robust quality management systems, such as ISO certifications, and a transparent manufacturing process. Established companies often have dedicated export departments capable of handling international logistics and documentation efficiently. When you purchase Venlafaxine Hydrochloride from a reputable Chinese supplier, you can expect competitive pricing without compromising on quality.

Procurement Strategies and Price Considerations

The price of Venlafaxine Hydrochloride can vary based on purity, order volume, and market dynamics. For bulk purchases, it's advisable to solicit quotes from multiple qualified suppliers. Building a direct relationship with a Venlafaxine Hydrochloride factory can often yield better pricing and more direct communication regarding production schedules and lead times. Consider the total cost of ownership, including shipping, import duties, and quality assurance measures.

Navigating the Supply Chain

Ensuring a stable supply chain is critical for pharmaceutical production. Working with a manufacturer that offers flexible packaging options, such as 25 kg fiber drums, and has proven logistical capabilities is essential. Reliable suppliers will also provide comprehensive Material Safety Data Sheets (MSDS) and Technical Data Sheets (TDS) to aid in handling and safety protocols. For companies looking to source Venlafaxine Hydrochloride, engaging with established chemical suppliers from China offers a strategic advantage in quality, cost, and availability.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a leading supplier of high-quality pharmaceutical intermediates, including Venlafaxine Hydrochloride. We invite you to contact us to discuss your specific needs and to obtain a quote for your next order.