Understanding the Specifications of Ethyl 2-Bromo-3-Methylbutyrate for Synthesis
For any chemical synthesis project, a thorough understanding of the raw materials' specifications is fundamental to achieving desired outcomes. Ethyl 2-Bromo-3-Methylbutyrate (CAS 609-12-1) is a prime example of an intermediate where precise specifications directly impact its performance and utility. This article aims to provide an overview of the critical specifications that researchers and procurement specialists should consider when purchasing this compound, highlighting the importance of purity, appearance, and other physical properties.
Ethyl 2-Bromo-3-Methylbutyrate, also known as Ethyl 2-Bromoisovalerate, is commonly used in organic chemistry for its reactivity as a halogenated ester. The most critical specification for its application in synthesis is purity. A typical assay requirement is 99.0% or higher, confirmed by Gas Chromatography (GC). This high purity ensures that unwanted side reactions are minimized, leading to cleaner product formation and higher yields. When you buy Ethyl 2-Bromo-3-Methylbutyrate, always verify the purity claims with a CoA from the manufacturer.
The appearance of Ethyl 2-Bromo-3-Methylbutyrate is also an important visual indicator of quality. It is generally described as a colorless liquid with a characteristic ester smell. Deviations from this description, such as discoloration or the presence of particulate matter, could indicate degradation or contamination, suggesting a need for caution or rejection of the batch. Suppliers based in China often adhere to strict quality control measures to ensure their products meet these visual and chemical standards.
Beyond purity and appearance, other physical properties are also relevant for synthesis planning. Key parameters include:
- Boiling Point: This is often provided at specific pressures, for example, 75-76°C/15mmHg, which is critical for distillation and purification processes.
- Density: Typically around 1.279-1.281 g/cm³.
- Refractive Index (nD20): Usually between 1.4497-1.4499, useful for identity confirmation.
- Water Content: Often specified as ≤0.02%, as excess water can interfere with certain reactions.
- Acidity: Measured as bromoisovaleric acid, with a maximum limit (e.g., 1.0% max).
For procurement managers and researchers looking to buy this chemical, understanding these specifications allows for informed decisions. Directly inquiring with manufacturers and suppliers about these details ensures that the purchased Ethyl 2-Bromo-3-Methylbutyrate aligns with the stringent requirements of your specific synthesis protocols. Reliable sourcing from reputable chemical suppliers, especially from China, guarantees access to intermediates with well-defined and verified specifications.
Perspectives & Insights
Silicon Analyst 88
“Deviations from this description, such as discoloration or the presence of particulate matter, could indicate degradation or contamination, suggesting a need for caution or rejection of the batch.”
Quantum Seeker Pro
“Suppliers based in China often adhere to strict quality control measures to ensure their products meet these visual and chemical standards.”
Bio Reader 7
“Beyond purity and appearance, other physical properties are also relevant for synthesis planning.”