For professionals in the pharmaceutical and fine chemical industries, the quality of chemical intermediates is a direct determinant of the success and safety of the final product. (2R,3S)-N-Boc-3-Phenylisoserine (CAS: 145514-62-1) is a high-value chiral intermediate, most notably used in the synthesis of Cabazitaxel. Understanding its key specifications is crucial for anyone looking to purchase this compound from a reliable manufacturer.

The appearance of (2R,3S)-N-Boc-3-Phenylisoserine is typically described as a white to off-white powder. This physical characteristic is a first indicator of product quality. More importantly, the assay value, commonly required to be ≥99.0% via HPLC, confirms the purity of the compound. High purity is non-negotiable for pharmaceutical applications, as even minor impurities can lead to complex side reactions or affect the biological activity of the final API. Researchers and procurement specialists should always verify the assay method and acceptance criteria.

Another critical specification is the specific rotation. For the (2R,3S) isomer, this value typically falls within the range of +48° to +52°. This parameter is a direct measure of the compound's enantiomeric purity, ensuring that the correct stereoisomer is being used in synthesis. Deviations from this range can indicate contamination with other isomers, rendering the batch unsuitable for chiral synthesis. When you buy this intermediate, always request the Certificate of Analysis (CoA) to confirm these specifications.

The molecular formula (C14H19NO5) and molecular weight (281.30400) are fundamental identifiers, while properties like density (1.239 g/cm³) and refractive index (1.547) provide further physical characterization. Understanding these details helps in assessing the material accurately. As a leading supplier, we ensure that all batches meet these demanding specifications, providing peace of mind for your synthesis projects.

When you are ready to buy (2R,3S)-N-Boc-3-Phenylisoserine, engaging with a supplier that provides comprehensive and accurate specification data is key. This commitment to quality assurance allows R&D scientists and formulators to proceed with confidence, knowing they are working with a superior intermediate, often at a competitive price when sourced directly from a manufacturer.