For any successful chemical synthesis, a thorough understanding of the starting materials is crucial. This includes not only their reactivity but also their physical properties, purity levels, and appropriate handling procedures. In this article, we focus on 1-Benzyl-1,4-Diazepane (CAS: 4410-12-2), a heterocyclic intermediate widely used in organic chemistry, detailing its key specifications and best practices for handling to ensure optimal results in your synthesis projects.

Essential Identification and Specifications

The foundational identifier for any chemical compound is its CAS number. For 1-Benzyl-1,4-Diazepane, this is 4410-12-2. Understanding its molecular formula (C12H18N2) and molecular weight (190.285) is also important for stoichiometric calculations in synthesis. Key physical specifications typically include:

  • Appearance: Colorless liquid. This visual characteristic is the first indicator of product quality.
  • Purity: Commonly specified as 95% minimum. For more demanding applications, higher purities (e.g., 98% or 99%) are available from specialized manufacturers. Always verify the CoA.
  • Melting Point (MP): While often presented as a liquid, its reported melting point range (54-56 °C) suggests it can solidify at lower ambient temperatures, impacting handling.
  • Boiling Point (BP): Approximately 93 °C. This is relevant for distillation or reactions conducted at elevated temperatures.
  • Density: Around 1.028 g/mL at 25 °C, useful for volumetric measurements.
  • Flash Point: Greater than 230 °F (>110 °C), indicating moderate flammability.

When you buy 1-Benzyl-1,4-Diazepane, reviewing these specifications from the manufacturer or supplier is a critical step to ensure it meets the requirements of your intended reaction.

Safe Handling and Storage Recommendations

Like many organic chemicals, proper handling and storage are essential for maintaining the integrity of 1-Benzyl-1,4-Diazepane and ensuring laboratory safety. Due to its liquid form and potential irritant properties (as indicated by H-statements like H315, H319, H335), it's imperative to:

  • Use Personal Protective Equipment (PPE): Always wear appropriate gloves, eye protection (safety glasses or goggles), and a lab coat. In situations with potential for aerosol generation, consider a respirator.
  • Ensure Adequate Ventilation: Handle the chemical in a well-ventilated area, preferably under a fume hood, to minimize inhalation exposure.
  • Avoid Contact: Prevent contact with skin, eyes, and clothing. In case of contact, follow the first-aid measures outlined in the SDS.
  • Storage Conditions: Keep the container tightly closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. While often stable at room temperature, following manufacturer-specific recommendations for prolonged storage is advised.

Procurement from Reliable Manufacturers

To secure high-quality 1-Benzyl-1,4-Diazepane with accurate specifications, it is best to purchase from reputable chemical manufacturers and suppliers. Companies offering detailed technical data sheets and Certificates of Analysis provide the transparency needed for effective R&D. When looking to buy, inquire about the manufacturer's quality control processes and their ability to provide consistent product batches. Sourcing from established Chinese manufacturers can often provide a cost-effective solution without compromising on the critical specifications required for successful chemical synthesis.

By adhering to these specifications and handling guidelines, chemists can confidently utilize 1-Benzyl-1,4-Diazepane in their synthesis, ensuring both the quality of their work and the safety of their laboratory environment.