For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, a thorough understanding of product specifications is fundamental to ensuring quality and successful outcomes. Methyl 3-Aminocrotonate (CAS 14205-39-1) is no exception. Its utility as a key intermediate, particularly in the synthesis of nicardipine and nitrendipine, demands adherence to strict quality standards.

The most commonly cited specification for Methyl 3-Aminocrotonate is its appearance: an off-white to light yellow crystalline powder. This visual characteristic is often the first indicator of product quality. Equally important is the assay, which typically specifies a minimum purity of 98.5% or 99%. A higher assay generally translates to fewer impurities, which is critical for sensitive synthesis reactions and regulatory compliance.

Other vital specifications include parameters like loss on drying (LOD) and residue on ignition. A low LOD, often specified as ≤0.5%, indicates minimal moisture content, crucial for product stability and accurate weighing in formulations. Similarly, a low residue on ignition (≤0.1%) points to the absence of inorganic impurities. Related substances, with limits on main single and total impurities, are also key indicators of the manufacturer's control over the synthesis process.

When you are ready to buy Methyl 3-Aminocrotonate, always request detailed specifications from potential suppliers. A reputable manufacturer will provide comprehensive documentation, including CoAs that clearly outline these parameters. Understanding these specifications helps in selecting the right grade of Methyl 3-Aminocrotonate for your specific application, whether it's for research, pilot scale, or large-scale production. Partnering with a trusted supplier who can consistently meet these quality benchmarks is essential for efficient procurement and reliable manufacturing.

By focusing on these key specifications, you can ensure that the Methyl 3-Aminocrotonate you procure from manufacturers meets the high standards required for pharmaceutical and fine chemical applications, safeguarding your product quality and development timelines.