For procurement managers and R&D scientists in the pharmaceutical industry, understanding the detailed specifications and pricing dynamics of critical intermediates is fundamental to successful sourcing. 1-(4-Methoxyphenyl)-2-benzylaminopropane (CAS 43229-65-8) is one such intermediate, vital for the synthesis of various APIs, particularly those targeting the central nervous system. As a leading manufacturer and supplier, we aim to provide clarity on these aspects.

Key Specifications for 1-(4-Methoxyphenyl)-2-benzylaminopropane (CAS 43229-65-8):

  • Chemical Name: 1-(4-Methoxyphenyl)-2-benzylaminopropane
  • CAS Number: 43229-65-8
  • Molecular Formula: C17H21NO
  • Molecular Weight: 255.36 g/mol
  • Appearance: Typically described as a yellow to colorless oily liquid or white to off-white crystalline powder, depending on the specific grade and purification process.
  • Purity (HPLC): A critical specification, usually required at ≥99.0% for pharmaceutical applications. This ensures minimal impurities that could affect downstream reactions or the final API quality.
  • Water Content: Typically ≤0.2% (as determined by Karl Fischer titration), important for stability and reaction efficiency.
  • Residual Solvents: Compliant with ICH Q3C guidelines, indicating a controlled level of process solvents.
  • Heavy Metals: Usually ≤10 ppm, a standard requirement for pharmaceutical raw materials.

Quality Standards and Manufacturer Commitment:

At our manufacturing facility, we adhere to stringent quality control measures. This includes investing in advanced analytical equipment for purity testing (HPLC), residual solvent analysis, and heavy metal detection. We understand that for pharmaceutical intermediate suppliers and custom synthesis clients, consistency is key. Therefore, our processes are designed to ensure excellent batch-to-batch reproducibility, often complemented by thermal stability under inert atmospheres. Our commitment extends to providing comprehensive Certificates of Analysis (CoA) with each shipment, detailing all relevant specifications and analytical results. For buyers looking to purchase this intermediate, verifying these quality standards with the manufacturer is a primary step.

Factors Influencing Pricing and Procurement:

The price of 1-(4-Methoxyphenyl)-2-benzylaminopropane is influenced by several factors:

  • Raw Material Costs: Fluctuations in the prices of precursor chemicals directly impact the final intermediate's cost.
  • Purity Requirements: Higher purity grades necessitate more rigorous purification steps, which can increase production costs.
  • Scale of Production: Bulk purchases generally benefit from economies of scale, leading to lower per-unit pricing for manufacturers and wholesale buyers.
  • Manufacturing Technology: The adoption of advanced technologies, such as continuous flow chemistry, can influence efficiency and, consequently, pricing.
  • Regulatory Compliance: Adherence to GMP and other quality standards can add to manufacturing overheads but ensures market access and product reliability.

For businesses seeking to buy 1-(4-Methoxyphenyl)-2-benzylaminopropane, obtaining a detailed quote from us will provide insight into current market pricing based on your specific quantity and purity requirements. We emphasize transparent pricing and aim to offer competitive rates without compromising on the critical quality attributes demanded by the pharmaceutical industry. Engaging with us means partnering with a reliable manufacturer committed to delivering value and quality.