Understanding the Specifications: Purity and Storage of 3-Pyrrolidinone Hydrochloride
For any chemical intermediate, particularly one as critical as 3-Pyrrolidinone Hydrochloride (CAS: 3760-52-9) used in sensitive applications like pharmaceutical synthesis, understanding its specifications is paramount. Manufacturers and researchers alike must be privy to details such as purity, solubility, and recommended storage to ensure optimal performance and product integrity.
The primary application of 3-Pyrrolidinone Hydrochloride as a precursor for antibacterial agents, especially carbapenem derivatives, demands a high degree of purity. Typically, suppliers offer this compound with an assay of 97% or higher. This stringent purity level is crucial because impurities can interfere with complex synthetic reactions, potentially leading to lower yields, unwanted by-products, and ultimately, compromising the efficacy and safety of the final drug product. When you purchase 3-Pyrrolidinone Hydrochloride, always verify the purity through the supplier's Certificate of Analysis (COA).
Solubility is another critical specification that influences how a chemical is used in a process. 3-Pyrrolidinone Hydrochloride is known to be soluble in common polar organic solvents such as DMSO (Dimethyl Sulfoxide) and also in water. This dual solubility makes it a versatile intermediate, allowing for flexibility in reaction medium selection, whether in aqueous or organic-based synthesis pathways. This characteristic is highly valued by R&D scientists when designing synthesis routes.
Storage conditions play a significant role in preserving the quality and shelf-life of chemical compounds. For 3-Pyrrolidinone Hydrochloride, the recommended storage temperature is typically in a freezer, below -20°C, and it should be kept under an inert atmosphere. This is often due to its sensitivity to moisture and potential degradation when exposed to air or higher temperatures. Adhering to these storage guidelines, as provided by the manufacturer or supplier, is essential to maintain the compound's chemical integrity. If you are looking to buy 3-Pyrrolidinone Hydrochloride in bulk, understanding these storage requirements is vital for your warehousing strategy.
When sourcing this compound from a manufacturer in China, like NINGBO INNO PHARMCHEM CO.,LTD., it is important to inquire about these specifications upfront. Knowing the exact purity, solubility profiles, and proper handling/storage instructions will not only help in planning your experimental procedures but also in negotiating a fair price. A transparent supplier will readily share this detailed information, reinforcing their commitment to delivering high-quality chemical products.
In summary, the specifications of 3-Pyrrolidinone Hydrochloride – its high purity, versatile solubility, and specific storage needs – are fundamental to its successful application. Diligent attention to these details ensures that researchers and manufacturers can effectively leverage this important intermediate for their critical synthetic processes.
Perspectives & Insights
Bio Analyst 88
“In summary, the specifications of 3-Pyrrolidinone Hydrochloride – its high purity, versatile solubility, and specific storage needs – are fundamental to its successful application.”
Nano Seeker Pro
“Diligent attention to these details ensures that researchers and manufacturers can effectively leverage this important intermediate for their critical synthetic processes.”
Data Reader 7
“For any chemical intermediate, particularly one as critical as 3-Pyrrolidinone Hydrochloride (CAS: 3760-52-9) used in sensitive applications like pharmaceutical synthesis, understanding its specifications is paramount.”