The chemical intermediate 7-Chloro-2-methylquinoline (CAS 4965-33-7) is a compound of significant interest due to its versatile applications, particularly in pharmaceutical synthesis. Understanding its synthesis and chemical properties is key to harnessing its full potential. NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in the production and supply of this essential compound.

The synthesis of 7-Chloro-2-methylquinoline typically involves the chlorination of 2-methylquinoline. This process requires precise control of reaction conditions to ensure selective chlorination at the desired 7th position, yielding a high-purity product. Advanced manufacturing techniques, including continuous flow processes, are often employed by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. to optimize yield and purity. These sophisticated methods ensure that the compound meets the stringent quality standards required for its downstream applications, especially in the pharmaceutical sector. The efficiency and scalability of these synthetic routes are critical for meeting global demand.

The chemical properties of 7-Chloro-2-methylquinoline are what make it such a valuable intermediate. With a molecular formula of C10H8ClN and a molecular weight of approximately 177.63 g/mol, it presents as a pale yellow to light beige crystalline powder. Its melting point typically falls within the range of 74-78°C, and its boiling point is noted at 87°C under reduced pressure (0.5 mmHg). The compound exhibits solubility in organic solvents such as ethanol and dichloromethane, but is only slightly soluble in water. This solubility profile aids in its handling and purification during various chemical processes. The presence of the chlorine atom and the methyl group on the quinoline ring provides specific reactivity that is leveraged in complex organic syntheses.

Furthermore, the compound's stability is maintained under standard room temperature and dry conditions, protected from light, which is important for storage and transportation. Safety information indicates that it can be harmful if swallowed and is a skin, eye, and respiratory irritant, necessitating appropriate handling precautions, including personal protective equipment and adequate ventilation. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive safety data sheets to ensure the safe use of their products. The ability to accurately characterize and control these chemical properties is fundamental to the reliable performance of 7-Chloro-2-methylquinoline in applications ranging from drug synthesis to the development of advanced materials.