Ethyl 6,8-dichlorooctanoate (CAS 1070-64-0) is a chemical compound of significant importance, particularly within the pharmaceutical and fine chemical industries. Its molecular structure, C10H18Cl2O2, and a molecular weight of 241.15, make it a versatile intermediate. Understanding its synthesis, properties, and applications is key for anyone involved in the procurement or utilization of this vital chemical.

Chemical Properties and Specifications

As a chemical intermediate, Ethyl 6,8-dichlorooctanoate is characterized by its appearance, typically ranging from colorless to pale yellow oil. Its chemical properties are crucial for its role in synthesis. Purity levels often cited are 97% minimum, with many suppliers offering higher grades such as 99% or 99.5% to meet the stringent demands of pharmaceutical applications. When sourcing this chemical, it's important to ensure it meets established quality standards, such as USP, BP, EP, or FCC, depending on the intended end-use.

Synthesis Pathways for Ethyl 6,8-dichlorooctanoate

The synthesis of Ethyl 6,8-dichlorooctanoate can be achieved through various chemical routes. One common method involves the chlorination of precursor molecules, such as ethyl 8-chloro-6-hydroxyoctanoate, using chlorinating agents like thionyl chloride or phosgene in the presence of suitable catalysts or acid-binding agents. The process typically involves careful temperature control and purification steps, often including vacuum distillation, to achieve high yields and purity. Manufacturers often refine these processes to optimize product quality and reduce production costs, making it more accessible for buyers looking to purchase this intermediate.

Applications in Pharmaceutical and Beyond

The primary application of Ethyl 6,8-dichlorooctanoate is as a critical intermediate in the synthesis of Alpha-Lipoic Acid (ALA). ALA is a naturally occurring antioxidant that plays a vital role in cellular metabolism and is used in dietary supplements and pharmaceuticals to combat oxidative stress and support nerve health. Beyond ALA, this compound may also find utility in the synthesis of Thioctamide and other specialty organic molecules. For those seeking to buy Ethyl 6,8-dichlorooctanoate for these applications, reliable sourcing from experienced manufacturers is essential.

Procurement Considerations and Market Access

When considering the purchase of Ethyl 6,8-dichlorooctanoate, potential buyers should investigate leading manufacturers and suppliers, particularly those based in China, known for their competitive pricing and production capabilities. Understanding 'Ethyl 6,8-dichlorooctanoate price' and 'where to buy CAS 1070-64-0' are common search queries for procurement professionals. Engaging directly with suppliers for quotes and product specifications ensures you obtain the right quality and quantity for your manufacturing needs. A reputable supplier will provide comprehensive product data, including MSDS and CoA, to support your purchasing decisions.

In summary, Ethyl 6,8-dichlorooctanoate is a chemical cornerstone for producing essential pharmaceuticals. By understanding its synthesis and applications, and by partnering with reliable manufacturers, businesses can ensure a consistent and high-quality supply of this crucial intermediate.