For chemists and researchers in organic synthesis, the availability of versatile building blocks is fundamental to innovation. 1,3-Dimethyl-1H-pyrazol-5-amine (CAS 3524-32-1) stands out as a valuable heterocyclic compound with a wide range of applications, particularly in the pharmaceutical and agrochemical sectors. Understanding its chemical properties and reactivity is key to leveraging its potential in new product development.

Chemical Properties and Reactivity Profile

1,3-Dimethyl-1H-pyrazol-5-amine is characterized by its pyrazole ring system, featuring two methyl groups and an amine substituent. This structure imparts unique chemical properties, including its nature as a basic amine and its potential for electrophilic aromatic substitution on the pyrazole ring. It is typically supplied as a light orange crystalline powder and is known to be hygroscopic, requiring proper storage in a dry environment. Its melting point, generally between 65-69 °C, is a key physical characteristic for identification and quality control when you buy this chemical.

Key Roles in Chemical Synthesis

The amine group on the pyrazole ring of 1,3-Dimethyl-1H-pyrazol-5-amine is highly reactive and serves as a primary nucleophile. This makes it an excellent starting material for a variety of reactions:

  • Amide Formation: Reacting with carboxylic acids or acid chlorides to form amide linkages, common in many drug molecules.
  • Alkylation and Acylation: The amine nitrogen can be readily alkylated or acylated to introduce new functional groups.
  • Cyclization Reactions: Its structure makes it suitable for cyclocondensation reactions, leading to more complex heterocyclic systems, such as pyrazolopyridines or other fused ring structures, often explored by pharmaceutical intermediate manufacturers.
  • Diazotization: The primary amine can undergo diazotization, opening pathways to further functionalization, such as Sandmeyer-type reactions.

As a reliable supplier, we aim to provide researchers and procurement specialists with high-purity 1,3-Dimethyl-1H-pyrazol-5-amine to facilitate these diverse synthetic endeavors. Sourcing this compound from a trusted manufacturer in China ensures quality and cost-effectiveness for your research and development efforts.

Whether you are developing new pharmaceutical intermediates, novel agrochemicals, or specialized materials, 1,3-Dimethyl-1H-pyrazol-5-amine (CAS 3524-32-1) offers a versatile platform. We encourage you to buy this essential building block and explore its transformative potential in your synthetic chemistry projects.