The world of organic chemistry is built upon a foundation of versatile building blocks, and 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone (CAS: 204205-33-4) stands out as a significant intermediate. Its unique structural features allow for its application in a range of synthesis pathways, most notably in the pharmaceutical industry. For researchers and procurement specialists looking to buy this compound, understanding its synthesis and applications is key to making informed sourcing decisions.

Synthesis Pathways and Chemical Properties

The synthesis of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone typically involves the bromination of its precursor, 1-cyclopropyl-2-(2-fluorophenyl)ethanone. Various methods can be employed, often utilizing brominating agents like iodine monobromide under controlled reaction conditions. The resulting product is characterized by its molecular formula C11H10BrFO and a molecular weight of approximately 257.10 g/mol. Typically presenting as a light yellow to brown liquid, its high purity (≥98%) is crucial for its intended applications. Other physical properties, such as density and boiling point, further define its chemical behavior and handling requirements.

Primary Application: Prasugrel Synthesis

One of the most prominent applications of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone is its role as a key intermediate in the synthesis of Prasugrel hydrochloride. Prasugrel is a vital antiplatelet medication used to prevent thrombotic events in patients with cardiovascular conditions. The structural integrity and purity of this intermediate directly impact the yield and quality of the final API. Therefore, reliable sourcing from a reputable manufacturer is critical for pharmaceutical production.

Broader Applications in Organic Synthesis

Beyond its pharmaceutical relevance, 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone also serves as a valuable reagent in broader organic synthesis. It can be utilized in the development of potent anti-oxidant agents and other complex organic molecules. Its reactive bromine atom and the presence of the fluorophenyl and cyclopropyl groups offer diverse possibilities for further chemical transformations. For research laboratories exploring new compound libraries or developing novel chemical entities, having access to this versatile intermediate from a trusted supplier is invaluable.

Procurement Considerations for Researchers and Buyers

When considering the purchase of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone, several factors come into play. These include the purity specifications (e.g., ≥98%), the availability of certificates of analysis (CoA), and the reputation of the manufacturer. Researchers often search for terms like 'buy 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone', 'CAS 204205-33-4 supplier', or 'Prasugrel intermediate price'. Engaging with experienced suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that you receive high-quality material, competitive price, and reliable delivery.

Conclusion

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone is a compound of significant importance, bridging synthesis pathways from basic organic chemistry to life-saving pharmaceuticals. Understanding its synthesis, chemical properties, and applications is crucial for anyone involved in its procurement. By partnering with a capable manufacturer and supplier, you can secure this essential intermediate to drive your research and production goals forward.