The Synthesis and Applications of 2,6-Dichloropurine Riboside in Drug Discovery
The journey from raw chemical to life-saving medication is complex, often relying on key intermediates that enable intricate synthesis processes. 2,6-Dichloropurine Riboside (CAS: 13276-52-3) is one such critical compound, playing a vital role in the development of pharmaceuticals designed to combat a range of severe diseases. As a dedicated manufacturer and supplier, we delve into its synthesis and applications, highlighting its importance for the R&D community.
The synthesis of 2,6-Dichloropurine Riboside can be achieved through several organic chemistry routes. One common method involves the diazotization of the 2-position amino group in a precursor like 2-amino-6-chloropurine nucleoside, followed by substitution with chloride ions. Another approach might involve condensing a mercury salt of 2,6-dichloropurine with a protected ribose derivative. These multi-step processes require precise control over reaction conditions, temperature, and reagents to achieve optimal yields and purity, ensuring the compound meets the high standards required for pharmaceutical use.
The chemical properties of 2,6-Dichloropurine Riboside, including its purity (typically ≥99.0%) and stability, make it a sought-after intermediate. Its molecular formula, C10H10Cl2N4O4, and molecular weight of 321.11700, define its chemical identity, while physical attributes like its appearance as a white or off-white crystalline powder provide essential handling information. These details are crucial for scientists and procurement managers when evaluating potential sources to buy this compound.
The primary utility of 2,6-Dichloropurine Riboside lies in its extensive applications within the pharmaceutical industry. It serves as a fundamental building block for the synthesis of:
- Antiviral Drugs: Essential for creating agents that inhibit viral replication, crucial for treating infections caused by various viruses.
- Antibacterial Agents: Utilized in the development of new drugs to combat bacterial infections, addressing the growing challenge of antibiotic resistance.
- Antitumor Medications: A key intermediate in the synthesis of cancer therapies, contributing to the discovery of more effective treatments.
For researchers and pharmaceutical companies, securing a reliable supplier in China for this intermediate is often the most strategic choice. We offer competitive pricing and robust supply chain management. We encourage potential clients to reach out for a detailed quote and product sample to verify our commitment to quality and service. Understanding the synthesis and application of such intermediates is paramount for driving innovation in drug discovery and ensuring the availability of vital medications worldwide.
By providing high-quality 2,6-Dichloropurine Riboside, we aim to support the critical work of pharmaceutical researchers and manufacturers, contributing to the development of treatments that improve global health outcomes.
Perspectives & Insights
Chem Catalyst Pro
“One common method involves the diazotization of the 2-position amino group in a precursor like 2-amino-6-chloropurine nucleoside, followed by substitution with chloride ions.”
Agile Thinker 7
“Another approach might involve condensing a mercury salt of 2,6-dichloropurine with a protected ribose derivative.”
Logic Spark 24
“These multi-step processes require precise control over reaction conditions, temperature, and reagents to achieve optimal yields and purity, ensuring the compound meets the high standards required for pharmaceutical use.”