The field of organic synthesis is constantly evolving, driven by the need for more effective and sustainable chemicals. Among the multitude of intermediates available, 3-Bromo-1H-Pyrazole (CAS 14521-80-3) has emerged as a compound of significant interest for its utility in creating advanced molecules. As a dedicated supplier and manufacturer, we aim to elucidate the synthesis pathways and application spectrum of this vital fine chemical.

Synthesis Routes for 3-Bromo-1H-Pyrazole

The preparation of 3-Bromo-1H-Pyrazole typically involves several established chemical routes. One common method described in literature involves the synthesis from pyrazole itself or through various substituted pyrazoles. For instance, a general procedure might involve a multi-step synthesis starting from readily available materials, often culminating in a bromination step to introduce the bromine atom at the desired position on the pyrazole ring. Another documented approach involves the deprotection of a protected 3-bromopyrazole derivative, such as 3-bromo-N,N-dimethyl-1H-pyrazole-1-sulfonamide, using trifluoroacetic acid. The resulting crude product is then purified, commonly through silica gel column chromatography, to yield the target compound.

Understanding these synthesis methods is crucial for manufacturers and researchers who might be looking to optimize production or explore novel synthetic strategies. The purity of the final product, typically stated as 97% or higher, is a direct result of these controlled synthetic and purification processes.

Diverse Applications Driving Demand

The chemical structure of 3-Bromo-1H-Pyrazole (C3H3BrN2, MW: 146.97 g/mol) makes it a highly versatile intermediate with significant applications in key industries:

  • Agrochemical Industry: Its most prominent use is as a precursor for the synthesis of Rynaxypyr, a potent insecticide. Rynaxypyr's effectiveness as a ryanodine receptor activator makes it a critical component in modern crop protection strategies, driving the demand for reliable suppliers of 3-Bromo-1H-Pyrazole.
  • Pharmaceutical Industry: As a pharmaceutical intermediate, it serves as a foundational building block for a wide range of drug candidates. Its heterocyclic nature and bromine substituent allow for diverse chemical modifications, facilitating the discovery of new therapeutic agents. Researchers often query 'pharmaceutical building blocks supplier' to source this compound.
  • Organic Synthesis and Research: The compound is widely used in academic and industrial research laboratories for custom synthesis projects, enabling the exploration of new chemical entities and materials.

Sourcing and Pricing Considerations

For businesses looking to procure 3-Bromo-1H-Pyrazole, searching for '3-bromopyrazole price' and identifying 'where to buy 3-bromopyrazole in China' are common initial steps. As a direct manufacturer and supplier, we offer competitive pricing and a commitment to quality. Our aim is to provide researchers and procurement managers with a seamless sourcing experience, whether for R&D quantities or bulk industrial orders.

We encourage you to reach out to us to discuss your specific requirements for 3-Bromo-1H-Pyrazole. Our team is ready to provide detailed product information, pricing, and to facilitate sample orders, ensuring you have access to this essential intermediate for your next chemical innovation.