For the dedicated R&D scientist, the pursuit of novel synthesis routes and the creation of complex molecular structures is at the heart of innovation. 3-Fluoro-2-formylpyridine (CAS 31224-43-8) is a compound that offers exciting possibilities due to its unique chemical architecture, serving as a valuable tool in advanced organic synthesis. Its utility spans various research domains, from pharmaceutical development to materials science.

The Reactivity Landscape of 3-Fluoro-2-formylpyridine
The key to 3-Fluoro-2-formylpyridine's synthetic versatility lies in its two primary functional groups: the aldehyde and the fluorinated pyridine ring. The aldehyde group is a well-known electrophile, readily participating in a wide range of nucleophilic addition and condensation reactions. This includes:

  • Wittig and Horner-Wadsworth-Emmons Reactions: For the formation of carbon-carbon double bonds.
  • Reductive Amination: To synthesize diverse amine derivatives.
  • Grignard and Organolithium Additions: To form secondary alcohols.
  • Condensation Reactions: Such as Knoevenagel condensation for creating unsaturated systems.

The presence of the fluorine atom on the pyridine ring also influences the electron distribution and reactivity of the entire molecule, often increasing metabolic stability or altering binding affinities in biologically active compounds. The pyridine nitrogen itself can also act as a nucleophile or ligand in certain catalytic processes.

Sourcing for Research Needs
To effectively explore these synthesis applications, researchers need access to high-quality 3-Fluoro-2-formylpyridine. NINGBO INNO PHARMCHEM CO.,LTD., as a leading manufacturer and supplier in China, provides this compound with a minimum purity of 98%. This ensures that your experimental results are reproducible and that the intended synthetic transformations occur efficiently. We understand the importance of reliable reagents for scientific discovery and offer competitive prices, even for smaller R&D quantities.

Partnering for Discovery
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting scientific advancement by providing essential chemical building blocks. If your research involves complex organic synthesis, and you are looking to buy 3-Fluoro-2-formylpyridine, our team is ready to assist you. We aim to be your trusted source for innovative chemical intermediates, facilitating your journey from laboratory synthesis to potential commercial applications.