3-Phenylpropanoyl Chloride, identified by CAS number 645-45-4, is a chemical compound widely recognized for its utility in organic synthesis. Often referred to as Hydrocinnamoyl Chloride, this acyl halide is a cornerstone in the preparation of a myriad of organic molecules, particularly within the pharmaceutical and fine chemical industries. Understanding its synthesis and diverse applications is vital for procurement managers and R&D scientists seeking reliable building blocks.

The synthesis of 3-Phenylpropanoyl Chloride typically involves the conversion of its corresponding carboxylic acid, 3-phenylpropanoic acid, into the acid chloride. A common and effective method involves reacting 3-phenylpropanoic acid with chlorinating agents such as oxalyl chloride or thionyl chloride. For example, a standard laboratory procedure might involve dissolving the acid in a solvent like dichloromethane, adding a catalytic amount of dimethylformamide (DMF), and then slowly adding oxalyl chloride. The reaction proceeds at room temperature, and after completion, the product is isolated by removing the solvent. This process ensures a high yield of the desired 3-Phenylpropanoyl Chloride.

The applications of this intermediate are extensive. In the pharmaceutical sector, it serves as a crucial building block for APIs, including those with antimicrobial or central nervous system activity. Its reactive nature allows for the straightforward formation of esters and amides, which are common functional groups in many drug molecules. For companies looking to buy 3-phenylpropanoyl chloride, recognizing its role as a key pharmaceutical intermediate is paramount.

As a dedicated manufacturer and supplier in China, we offer high-purity 3-Phenylpropanoyl Chloride, ensuring consistent quality for your chemical synthesis needs. When you inquire about the 3-phenylpropanoyl chloride price, you can expect competitive rates reflecting our efficient production processes. Our commitment as a reliable supplier means you can depend on us for timely delivery and quality assurance, making us an ideal partner for your chemical sourcing requirements.

Beyond pharmaceuticals, 3-Phenylpropanoyl Chloride is also utilized in the synthesis of agrochemicals and as a modifier in polymer chemistry. Its potential use in organic electronics further highlights its versatility. Whether you are developing a new drug, enhancing an agricultural product, or exploring novel materials, securing a dependable source for 3-Phenylpropanoyl Chloride is essential. Contact us today to discuss your specific requirements and learn more about our high-quality chemical intermediates.