In the dynamic field of chemical synthesis, intermediates that offer unique reactivity and structural features are highly sought after. 4'-Bromomethyl-2-cyanobiphenyl, identified by CAS number 114772-54-2, is one such compound, prized for its utility in pharmaceutical synthesis and broader organic chemistry applications. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier of this critical intermediate, dedicated to providing high-quality products to researchers and industries worldwide.

The synthesis of 4'-Bromomethyl-2-cyanobiphenyl typically involves the chemical transformation of readily available precursors, such as 2-cyano-4-methylbiphenyl. Common methods often employ brominating agents under controlled conditions, ensuring the selective addition of bromine to the methyl group. For example, reactions involving dibromohydantoin at specific temperatures, followed by purification steps like recrystallization, can yield the desired product with high purity, often exceeding 98.0% (GC). Understanding these synthesis routes is vital for procurement managers and chemists who need to ensure the quality and consistency of the materials they buy.

The primary applications of 4'-Bromomethyl-2-cyanobiphenyl lie in its role as a key intermediate in the synthesis of important pharmaceutical drugs. It is a crucial building block for the 'sartan' class of medications, widely used to treat hypertension and heart conditions. Specifically, it is integral to the production of APIs like azilsartan ester and temisartan. Its reactive bromomethyl group also makes it a versatile reagent for introducing the cyanobiphenyl moiety into other complex organic molecules, finding use in various research and development projects. Furthermore, its use as a reference standard for impurity profiling in drug analysis highlights its multifaceted importance.

For companies looking to source this intermediate, reliability and quality are paramount. NINGBO INNO PHARMCHEM, as a prominent chemical supplier in China, offers 4'-Bromomethyl-2-cyanobiphenyl with guaranteed high purity and competitive pricing. We understand the stringent requirements of the pharmaceutical and fine chemical industries and are equipped to meet the demands of both small-scale research and large-scale industrial production. When you choose to buy from us, you are selecting a partner committed to excellence in chemical manufacturing and supply chain management.

We encourage R&D scientists and procurement specialists to inquire about our offerings. Whether you need this compound for the synthesis of established drugs, the development of new chemical entities, or as an analytical standard, NINGBO INNO PHARMCHEM is your reliable source. Contact us for a quote and to learn more about how we can support your chemical sourcing needs for 4'-Bromomethyl-2-cyanobiphenyl.