The chemical industry continuously seeks novel compounds and efficient synthesis pathways to drive innovation, particularly in pharmaceuticals. 6-Iodo-1H-indazole (CAS: 261953-36-0) is a prime example of a valuable intermediate with significant applications in organic synthesis and drug development. As a leading manufacturer and supplier, we are committed to providing insights into the compound’s properties, synthesis, and the broad spectrum of its applications.

Chemically speaking, 6-Iodo-1H-indazole is a white powder characterized by its indazole core with an iodine atom at the 6-position. Its molecular formula is C7H5IN2, with a molecular weight of 244.03. The synthesis of this compound typically involves iodination reactions, often starting from precursor molecules such as 6-bromo-1H-indazole or 6-amino-1H-indazole. Various catalytic systems and reaction conditions are employed to achieve high yields and purity, typically exceeding 98.0% assay. For instance, copper(I) iodide catalyzed reactions in dioxane have been documented as effective routes, highlighting the technical expertise required for its production.

The applications of 6-Iodo-1H-indazole are diverse and impactful. Primarily, it serves as a critical pharmaceutical intermediate, forming the backbone for synthesizing various active pharmaceutical ingredients (APIs). Its structure is particularly relevant in the development of kinase inhibitors, which are crucial in cancer therapy, such as Axitinib. Beyond pharmaceuticals, it finds utility in broader organic synthesis, acting as a versatile building block for creating complex heterocyclic compounds and advanced materials. Researchers engaged in drug discovery or material science often seek to purchase this compound for its unique reactivity and potential.

For any research or manufacturing entity looking to buy 6-Iodo-1H-indazole, partnering with a reliable manufacturer is paramount. We offer this high-purity intermediate, ensuring that your synthesis projects benefit from consistent quality and a stable supply. Whether you are in the early stages of research or require larger quantities for production, understanding the synthesis processes and application potential of 6-Iodo-1H-indazole empowers informed purchasing decisions. We are your trusted source for this essential fine chemical, supporting your scientific and commercial objectives.