Diethyl Aminomalonate Hydrochloride (CAS 13433-00-6) is a chemical compound of significant interest, particularly within the pharmaceutical and fine chemical industries. Its utility stems from its role as a key intermediate in the synthesis of a variety of valuable compounds, most notably pyrimidine heterocyclic structures. Understanding its synthesis and application is crucial for chemists and procurement professionals looking to leverage its potential. As a dedicated manufacturer and supplier, we offer insights into this important chemical.

The synthesis of Diethyl Aminomalonate Hydrochloride typically involves the reduction of diethyl iminomalonate or related precursors, followed by treatment with hydrochloric acid. Sources indicate that starting materials like diethyl hydroxyiminomalonate can be hydrogenated in the presence of a catalyst, such as palladium on charcoal, under hydrogen pressure. The subsequent addition of dry hydrogen chloride facilitates the isolation and purification of the desired hydrochloride salt. This process yields a white crystalline powder, commonly with a purity of 98% or higher, making it suitable for demanding applications. We offer this compound, ready for your use.

The applications of Diethyl Aminomalonate Hydrochloride are primarily centered around its role as a versatile pharmaceutical intermediate. It is widely used in the production of pyrimidine derivatives, which are integral to many drug molecules, including those used in oncology and as antiviral agents. The compound's amino group and ester functionalities allow for a range of chemical transformations, making it a valuable component in complex synthetic routes. For researchers and manufacturers, understanding how to effectively buy and utilize this intermediate is key to achieving efficient and successful synthesis outcomes.

For businesses seeking to procure Diethyl Aminomalonate Hydrochloride, partnering with a reliable supplier is essential. We provide consistent quality and volume, ensuring that your production or research needs are met. Our expertise in chemical manufacturing and supply chain management allows us to serve as a trusted source for this critical intermediate. We encourage inquiries for quotes and samples, facilitating the integration of our high-quality Diethyl Aminomalonate Hydrochloride into your projects, whether for laboratory research or industrial-scale manufacturing.