The advancement of organic chemistry is continuously fueled by the development and application of sophisticated reagents. Among these, 2-Chloro-4,6-dimethoxy-1,3,5-triazine, widely known as CDMT (CAS 3140-73-6), has carved a significant niche as a highly effective coupling agent. This article provides an in-depth look at CDMT, covering its synthesis, chemical characteristics, and its broad spectrum of applications, offering valuable insights for researchers and formulators looking to buy this versatile chemical.

Understanding CDMT: Synthesis and Properties

CDMT is synthesized through established chemical routes, often starting from cyanuric chloride. Its molecular formula is C5H6ClN3O2, with a molecular weight of approximately 175.57 g/mol. Typically appearing as a white crystal powder, CDMT exhibits good solubility in common organic solvents such as THF, DCM, and DMF, which facilitates its use in various reaction media. A key feature of CDMT is its stability under recommended storage conditions, usually in a cool, dry environment under an inert atmosphere.

The primary utility of CDMT lies in its ability to activate carboxylic acids for subsequent nucleophilic attack. This activation process enables the efficient formation of amide and ester bonds, making it a favored reagent in peptide synthesis, the preparation of Weinreb amides, and lactamization reactions. For scientists and procurement specialists aiming to purchase this reagent, understanding its chemical properties is crucial for optimizing experimental design and ensuring successful synthesis outcomes.

Diverse Applications of CDMT: Beyond Peptide Synthesis

  • Peptide Chemistry: CDMT is a cornerstone for synthesizing peptides, offering high yields and excellent stereochemical retention.
  • Active Pharmaceutical Ingredients (APIs): Its use as a key intermediate in API synthesis highlights its importance in the pharmaceutical industry.
  • Fine Chemical Synthesis: CDMT is valuable for creating a variety of complex organic molecules used in diverse chemical applications.
  • Organic Synthesis Research: Academic and industrial researchers frequently employ CDMT for its versatility and reliability in challenging coupling reactions.

Sourcing High-Quality CDMT

When you are ready to buy 2-Chloro-4,6-dimethoxy-1,3,5-triazine, partnering with a reputable manufacturer and supplier is essential. We are committed to producing CDMT with stringent quality control, ensuring high purity and consistent performance. Our manufacturing base in China allows us to offer this crucial reagent at competitive prices, supported by a reliable supply chain. We encourage you to contact us to discuss your specific requirements, obtain a quote, and learn more about how our CDMT can benefit your research and production needs.