For procurement professionals and research scientists in the chemical industry, the efficient and reliable acquisition of key synthesis intermediates is critical. 2-Bromo-5-fluorobenzonitrile (CAS 57381-39-2) represents such an intermediate, offering significant utility in the development of pharmaceuticals, agrochemicals, and advanced materials. This article serves as a guide to understanding its importance and navigating the procurement process.

Chemical Properties and Significance

2-Bromo-5-fluorobenzonitrile is a white crystalline powder with a high purity standard, commonly specified as ≥98.0%. This attribute is vital for ensuring the success of downstream synthesis reactions, minimizing unwanted side products, and achieving desired yields. Its molecular structure, featuring an electron-withdrawing nitrile group and halogen substituents on a benzene ring, provides multiple reaction sites. This makes it a highly versatile building block for complex organic synthesis. Its molecular formula is C7H3BrFN, with a molecular weight of 200.01.

Key Industrial Applications

The value of 2-Bromo-5-fluorobenzonitrile is evident across several high-impact industries:

  • Pharmaceutical Industry: It serves as a crucial intermediate in the synthesis of various drug compounds. Its utility in creating novel pharmaceutical agents, particularly those targeting specific biological pathways, makes it a sought-after material for drug discovery and development. When you buy 2-bromo-5-fluorobenzonitrile for this purpose, ensure the supplier meets stringent quality controls.
  • Agrochemical Sector: This compound plays a role in developing next-generation crop protection agents, such as herbicides and pesticides. Its structural features can contribute to the bioactivity and selectivity of these agricultural chemicals. Securing a stable supply from a reputable 2-bromo-5-fluorobenzonitrile manufacturer is important for production continuity.
  • Research and Development: In academic and industrial R&D settings, it is used as a versatile starting material for exploring new chemical reactions and synthesizing novel compounds with potential applications in various fields.

Procurement Best Practices

When it comes to sourcing 2-Bromo-5-fluorobenzonitrile, procurement managers should consider the following:

  • Supplier Vetting: Identify manufacturers and suppliers with a proven track record in producing high-purity fine chemicals. Checking for ISO certifications and adherence to quality management systems is advisable.
  • Purity Verification: Always request a Certificate of Analysis (COA) to confirm the product's purity (≥98.0%) and other relevant specifications.
  • Bulk Purchase Considerations: For industrial quantities, understand the supplier's production capacity and lead times. Obtaining multiple quotes can help secure the best price for 2-bromo-5-fluorobenzonitrile. We are a reliable supplier in China, capable of meeting large volume demands.
  • Regulatory Compliance: Ensure the supplier provides all necessary documentation, including Safety Data Sheets (SDS), for safe handling and transport.

In essence, 2-Bromo-5-fluorobenzonitrile is a cornerstone intermediate for many chemical synthesis endeavors. By understanding its applications and adopting a strategic approach to procurement, businesses can ensure they are well-equipped to drive innovation and maintain a competitive edge. We are dedicated to supporting your chemical needs with high-quality products and dependable service.