Lornoxicam, a potent non-steroidal anti-inflammatory drug (NSAID) widely used for pain and inflammation management, relies on a precise chemical synthesis pathway. Central to this process are key intermediates, among which Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate (CAS: 126910-68-7) plays a crucial role. Understanding the synthesis and the reliable sourcing of this intermediate is vital for pharmaceutical companies involved in Lornoxicam production.

The synthesis of Lornoxicam typically involves several steps, with Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate serving as a critical building block. This compound, characterized by its yellow powder appearance and a typical assay of ≥95.0% (HPLC), provides the necessary thiophene scaffold and reactive functional groups for subsequent chemical transformations. Pharmaceutical R&D scientists and production managers often search for 'buy Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate' or 'CAS 126910-68-7 Lornoxicam synthesis' to identify trusted manufacturers and suppliers.

For robust Lornoxicam manufacturing, securing a consistent supply of high-purity Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate is essential. Manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., specialize in producing these vital intermediates. They offer bulk supply with reliable quality control and competitive pricing, making them a preferred choice for global pharmaceutical companies. Their ability to provide custom synthesis also allows for tailoring the intermediate to specific production needs.

When inquiring about this intermediate, potential buyers should seek detailed product specifications, including purity, physical properties, and stability data. Requesting a quotation and samples allows for thorough evaluation before committing to a purchase. The price of Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate can vary based on volume and purity requirements, so clear communication with the supplier is key. By partnering with reputable manufacturers and understanding the importance of each synthetic step, pharmaceutical companies can ensure the efficient and high-quality production of Lornoxicam, ultimately benefiting patients worldwide.