The reliable production of key chemical intermediates is fundamental to supporting industries like pharmaceuticals and agrochemicals. Trans-1,2-Cyclohexanediol (CAS 1460-57-7) is a critical compound, and understanding its synthesis pathways is crucial for manufacturers and buyers alike. NINGBO INNO PHARMCHEM CO.,LTD., a prominent manufacturer based in China, provides insights into how this valuable organic intermediate is produced.

Common Synthesis Routes for Trans-1,2-Cyclohexanediol:

Several methods can be employed to synthesize Trans-1,2-Cyclohexanediol. The choice of route often depends on factors such as desired purity, cost-effectiveness, availability of starting materials, and environmental considerations. Some of the established pathways include:

  • Hydrogenation of Catechol Derivatives: While less common for direct trans isomer synthesis, modifications can lead to cyclohexanediols.
  • Hydroxylation of Cyclohexene: The addition of hydroxyl groups across the double bond of cyclohexene is a primary method. Often, this involves epoxidation followed by ring-opening, or direct dihydroxylation using agents like osmium tetroxide or potassium permanganate under controlled conditions that favor the trans product.
  • Reduction of Cyclohexane-1,2-dione: Reducing the diketone can yield the diol. Stereoselective reduction methods are often employed to favor the trans isomer.
  • Isomerization of Cis-1,2-Cyclohexanediol: In some cases, the cis isomer can be isomerized to the more stable trans form.

As a manufacturer, our focus is on optimizing these processes to ensure high yields, exceptional purity (99% min), and cost-efficiency. We invest in advanced manufacturing technologies and rigorous quality control to guarantee that the Trans-1,2-Cyclohexanediol we supply meets the exacting standards required by our customers. Our production is geared towards providing a consistent and reliable supply for those who need to buy this essential intermediate.

Why Purchase from NINGBO INNO PHARMCHEM?

When you choose to buy Trans-1,2-Cyclohexanediol from us, you benefit from our expertise in chemical synthesis and manufacturing. We understand the intricacies of producing high-quality intermediates and are committed to delivering products that support your research and production goals. Our aim is to be your trusted supplier, offering competitive pricing and dependable service for all your chemical needs. Contact us for a quotation and to learn more about our manufacturing capabilities.