Exploring the Synthesis and Properties of 2-Chloro-5-fluorobenzaldehyde
In the realm of industrial chemistry, understanding the synthesis and fundamental properties of key intermediates is essential for both efficiency and innovation. 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) is one such compound, widely recognized for its utility as a precursor in the manufacturing of pharmaceuticals, agrochemicals, and other fine chemicals. For procurement specialists and research scientists, a detailed grasp of its production and characteristics from reliable manufacturers is invaluable.
The synthesis of 2-Chloro-5-fluorobenzaldehyde typically involves multi-step organic reactions, often starting from readily available aromatic precursors. Common routes may include the selective halogenation of substituted benzaldehydes or the oxidation of corresponding benzyl alcohols. For example, one synthetic pathway might involve the careful chlorination and subsequent fluorination of a precursor, or vice versa, under controlled reaction conditions to achieve the desired regioselectivity. Another approach could involve the formylation of a suitably substituted halobenzene. The specific method chosen by a manufacturer can influence yield, purity, and the overall cost of production.
Key physicochemical properties of 2-Chloro-5-fluorobenzaldehyde contribute to its handling and application. It is typically described as an off-white crystalline solid, with a melting point in the range of 46.5-48°C. This solid form aids in its storage and transportation. Its molecular formula is C7H4ClFO, with a molecular weight of approximately 158.56 g/mol. The compound exhibits moderate solubility in common organic solvents, which is advantageous for its use in various reaction media. Detailed specifications, such as a purity of ≥99.0% (GC), are critical for end-users, particularly when engaged in precise synthetic processes.
When you search to 'buy 2-chloro-5-fluorobenzaldehyde', you are looking for a compound that has been synthesized to meet stringent quality standards. Manufacturers aim to minimize impurities that could interfere with subsequent reactions or affect the quality of the final product. Therefore, understanding the common synthesis routes and the resulting purity profiles is important for buyers. Reputable 'chemical intermediate suppliers' will readily provide this technical information.
The '2-chloro-5-fluorobenzaldehyde price' is often influenced by the complexity of its synthesis, the cost of raw materials, and the scale of production. Companies seeking to optimize their 'chemical synthesis' costs might look for manufacturers who have streamlined their production processes or who can offer competitive pricing for bulk orders. Engaging with a trustworthy 'fine chemical manufacturer' ensures not only quality but also consistency in supply and pricing, which are vital for industrial operations.
In conclusion, the synthesis and properties of 2-Chloro-5-fluorobenzaldehyde underscore its importance as a versatile intermediate. By understanding its production methods and physical characteristics, professionals can better evaluate suppliers and ensure they are obtaining a high-quality product for their demanding applications in the chemical and pharmaceutical industries.
Perspectives & Insights
Quantum Pioneer 24
“In the realm of industrial chemistry, understanding the synthesis and fundamental properties of key intermediates is essential for both efficiency and innovation.”
Bio Explorer X
“2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) is one such compound, widely recognized for its utility as a precursor in the manufacturing of pharmaceuticals, agrochemicals, and other fine chemicals.”
Nano Catalyst AI
“For procurement specialists and research scientists, a detailed grasp of its production and characteristics from reliable manufacturers is invaluable.”