For professionals in chemical synthesis, pharmaceutical development, and material science, understanding the fundamental properties and accessible synthesis methods of key intermediates is crucial. 3-(Dimethylamino)propanoic acid (CAS: 6300-04-5) is a compound that embodies this importance, offering a unique combination of functionalities. As a leading chemical supplier and manufacturer in China, we provide high-quality 3-(Dimethylamino)propanoic acid and insights into its production and characteristics.

Chemical Structure and Properties

3-(Dimethylamino)propanoic acid is classified as a beta-amino acid, meaning the amino group is attached to the beta-carbon relative to the carboxylic acid group. Its molecular formula is C5H11NO2, with a molecular weight of approximately 117.15 g/mol. Key properties include:

  • Appearance: Typically a colorless to light yellow solid-liquid mixture.
  • Melting Point: Approximately 143-146 °C.
  • Solubility: Soluble in water, facilitating its use in aqueous-based reactions and formulations.
  • Reactivity: Possesses the characteristic reactivity of both tertiary amines and carboxylic acids, enabling a wide range of chemical transformations such as esterification, amidation, and salt formation.
  • Acidity Factor (pKa): Predicted around 3.67 ± 0.14.

Synthesis Pathways

Several methods exist for synthesizing 3-(Dimethylamino)propanoic acid, ranging from classical approaches to more modern, greener techniques. Common routes include:

  • Michael Addition: The addition of dimethylamine to acrylic acid or its esters, often under controlled pH and temperature conditions.
  • Alkylation of Beta-Alanine: Reacting beta-alanine with methylating agents (like methyl iodide) in the presence of a base.
  • Reductive Amination: Employing reductive amination techniques with appropriate precursors and dimethylamine.

Advancements in green chemistry are also leading to more efficient and environmentally friendly synthesis methods, such as microwave-assisted reactions and catalytic processes that reduce waste and energy consumption.

Applications and Sourcing

This versatile intermediate finds use in peptide synthesis, pharmaceutical development, and material science. Its ability to introduce specific functionalities into molecules makes it invaluable for R&D. If you are looking to buy 3-(dimethylamino)propanoic acid, partnering with a reliable manufacturer and supplier is crucial.

As a reputable China-based manufacturer, we offer 3-(Dimethylamino)propanoic acid with guaranteed high purity and consistent quality. We provide competitive pricing and efficient service to meet your research and production needs. Contact us to inquire about purchasing this essential chemical intermediate and to discuss how our reliable supply chain can support your projects.