The efficacy of chemical synthesis often hinges on the quality and specific properties of the reagents used. 4-(Acetoxymethyl)benzoic Acid, often referred to as AC-HMBA Linker (CAS 15561-46-3), is a prime example of a specialized chemical intermediate valued for its well-defined structure and high purity. As a manufacturer dedicated to producing such critical compounds, understanding the synthesis and inherent properties of AC-HMBA Linker is key to appreciating its utility in various applications, especially in solid-phase synthesis and peptide chemistry.

Chemical Synthesis of AC-HMBA Linker

The synthesis of 4-(Acetoxymethyl)benzoic Acid typically begins with 4-(Hydroxymethyl)benzoic acid. This precursor undergoes an acetylation reaction, where the hydroxyl group (-OH) is converted into an acetoxy group (-OCOCH3). This transformation is commonly achieved using acetylating agents such as acetic anhydride or acetyl chloride, often in the presence of a catalyst. The reaction conditions are carefully controlled to ensure high yields and prevent unwanted side reactions, such as acetylation of the carboxylic acid group. The resulting product, AC-HMBA Linker, is then rigorously purified to meet the high-purity standards required by end-users.

Key Properties of AC-HMBA Linker

The chemical structure of AC-HMBA Linker is central to its functionality:

  • Molecular Formula: C10H10O4
  • Molecular Weight: 194.18 g/mol
  • Appearance: Typically a white to off-white solid powder.
  • Purity: We supply AC-HMBA Linker with a guaranteed purity of ≥97% (HPLC), ensuring its suitability for sensitive synthesis protocols.
  • Reactivity: The carboxylic acid group allows for facile formation of esters and amides, while the acetoxymethyl group can be selectively cleaved, releasing a hydroxymethyl group. This cleavage is often achieved under mild basic conditions.

Why Purchase from a Reliable Manufacturer?

When you decide to buy AC-HMBA Linker, opting for a manufacturer with a proven track record in producing high-purity chemicals is paramount. Our commitment to stringent quality control ensures that each batch of AC-HMBA Linker meets rigorous specifications. This is vital for applications like peptide synthesis, where even minor impurities can significantly affect the final product quality and yield. We offer competitive pricing and reliable delivery, making us your ideal partner for sourcing this critical chemical intermediate.

For research and development teams seeking high-quality AC-HMBA Linker, we provide the assurance of purity, consistent supply, and expert support. Contact us today to get a quote and discuss your bulk purchasing needs.