1-Bromo-4-propylbenzene (CAS 588-93-2) is a fundamental aromatic halide, characterized by its clear, colorless to pale yellow liquid appearance and a distinct set of chemical and physical properties that dictate its utility in various synthesis applications. For professionals in chemical procurement and R&D, a thorough understanding of these properties and common synthesis routes is vital for effective sourcing and utilization.

Chemically, 1-Bromo-4-propylbenzene is an aryl halide. Its molecular formula, C9H11Br, and molecular weight of approximately 199.09 g/mol, define its composition. A key feature is the bromine atom positioned para to the n-propyl group on the benzene ring. This configuration makes the bromine atom amenable to nucleophilic substitution and, more importantly, to palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings. These reactions are foundational in modern organic synthesis, enabling the construction of complex carbon frameworks.

Physically, the compound typically presents as a liquid with a boiling point around 220-222°C. Its density is approximately 1.26 g/cm³ at 25°C, and its refractive index is around 1.538-1.540. The flash point is reported around 96°C. These properties are crucial for handling, storage, and process design. For instance, the storage conditions often recommended are cool, dry places, sometimes under an inert atmosphere, to maintain purity and prevent degradation.

The synthesis of 1-Bromo-4-propylbenzene commonly involves electrophilic aromatic substitution or metal-catalyzed coupling reactions. One typical route involves the bromination of propylbenzene. Alternatively, it can be synthesized via Grignard reaction chemistry or other organometallic approaches starting from dibromobenzene derivatives. For example, a common industrial method might involve reacting 1,4-dibromobenzene with n-propyl magnesium bromide in the presence of a catalyst. These synthesis pathways are often optimized for yield and purity to meet industrial demands. When companies look to buy intermediates, they seek manufacturers with well-established and efficient production processes.

As a leading chemical manufacturer and supplier, understanding these synthesis details allows us to provide products of the highest quality. We ensure that our 1-Bromo-4-propylbenzene meets stringent purity standards, making it suitable for demanding applications in pharmaceutical synthesis, agrochemical development, and advanced material creation. Professionals looking to purchase chemical raw materials can rely on our expertise and commitment to quality.

Whether you are developing new pharmaceuticals, formulating advanced agrochemicals, or creating novel materials, the foundational properties and synthesis routes of 1-Bromo-4-propylbenzene are key considerations. We encourage you to inquire about our product specifications and bulk purchasing options to support your manufacturing and research goals.