For professionals in pharmaceutical research and development, the purity and synthetic accessibility of key chemical intermediates are of utmost importance. 1-Bromonaphthalen-2-amine (CAS: 20191-75-7) is a prime example of such a compound, serving as a fundamental building block in the creation of complex pharmaceutical agents. This article provides an overview of its synthesis, the significance of its purity, and its applications, emphasizing why sourcing from reputable manufacturers is critical.

1-Bromonaphthalen-2-amine is a naphthalene derivative distinguished by its chemical formula C10H8BrN and a molecular weight of 222.08 g/mol. It typically presents as a white powder with a purity standard of 98% minimum. This high purity is essential for R&D scientists as impurities can significantly affect reaction yields, product characterization, and the ultimate efficacy of the synthesized API. Manufacturers must employ rigorous quality control measures during its synthesis to achieve and maintain this purity level.

The synthesis of 1-bromonaphthalen-2-amine often involves carefully controlled bromination and amination steps on naphthalene precursors. Advanced synthetic methodologies are employed by manufacturers to ensure efficient production and minimize unwanted side products. For example, achieving regioselective bromination and subsequent amination at the correct positions on the naphthalene ring requires optimized reaction conditions and catalysts. Understanding these synthetic routes is beneficial for researchers when evaluating suppliers.

As a pharmaceutical intermediate, 1-bromonaphthalen-2-amine’s true value lies in its versatility in synthetic organic chemistry. It acts as a scaffold upon which more complex molecular structures can be built, leading to the development of new drug candidates. Its bromine substituent can participate in various cross-coupling reactions, while the amine group offers a site for further functionalization. These reactions are foundational in medicinal chemistry for creating diverse chemical libraries and exploring structure-activity relationships.

For organizations looking to buy 1-bromonaphthalen-2-amine, partnering with a trusted manufacturer, especially one based in China, can offer a strategic advantage. Chinese chemical suppliers often provide high-purity intermediates at competitive prices, supported by robust manufacturing capabilities. Access to consistent quality and reliable supply chains is paramount for both small-scale research projects and large-scale pharmaceutical production. Our company is committed to being that dependable source for your chemical needs.

In summary, 1-bromonaphthalen-2-amine is a critical intermediate for pharmaceutical R&D, prized for its purity and synthetic potential. Its reliable synthesis and consistent quality, offered by experienced manufacturers, are vital for driving innovation in drug discovery. By understanding its chemical characteristics and the importance of sourcing from qualified suppliers, research teams can ensure the success of their projects.