Exploring the Synthesis and Quality Control of Ethyl 6,7-difluoro-2-ethylmercapto-4-hydroxyquinoline-3-carboxylate
The production of high-quality pharmaceutical intermediates demands precision in synthesis and stringent quality control. Ethyl 6,7-difluoro-2-ethylmercapto-4-hydroxyquinoline-3-carboxylate (CAS: 154330-67-3), a key component in the manufacturing of the antibiotic Prulifloxacin, exemplifies these requirements. NINGBO INNO PHARMCHEM CO.,LTD. is committed to upholding the highest standards in both the synthesis and quality assurance of this crucial chemical compound, ensuring its suitability for advanced antibiotic synthesis.
The synthesis of Ethyl 6,7-difluoro-2-ethylmercapto-4-hydroxyquinoline-3-carboxylate involves complex organic chemical reactions that require careful control of parameters such as temperature, pressure, and reagent ratios. Manufacturers must ensure that the process yields a product with a high degree of purity, typically at least 98.0%, and the characteristic light yellow to off-white crystalline powder appearance. This meticulous approach to synthesis is fundamental for an intermediate used in pharmaceutical applications, especially for antibiotic synthesis where consistency is paramount.
Quality control is an integral part of the manufacturing process. Rigorous analytical testing, including techniques like High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and spectroscopy, is employed to verify the purity and identity of the compound. These tests confirm that the material meets the exact specifications required for its intended use as a Prulifloxacin intermediate. For pharmaceutical companies, working with suppliers who demonstrate robust quality control systems is essential for maintaining the integrity of their own production lines and for complying with regulatory standards in the pharmaceutical intermediate supply chain.
As a trusted pharmaceutical intermediate supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. understands the critical nature of its products. The company's commitment to advanced synthesis techniques and comprehensive quality assurance protocols ensures that Ethyl 6,7-difluoro-2-ethylmercapto-4-hydroxyquinoline-3-carboxylate is consistently available at the required purity and quality. This focus not only supports the production of essential antibiotics but also contributes to the broader advancement of medicinal chemistry and the development of new therapeutic agents, solidifying its role in fluoroquinolone antibiotic intermediate research.
Perspectives & Insights
Logic Thinker AI
“0%, and the characteristic light yellow to off-white crystalline powder appearance.”
Molecule Spark 2025
“This meticulous approach to synthesis is fundamental for an intermediate used in pharmaceutical applications, especially for antibiotic synthesis where consistency is paramount.”
Alpha Pioneer 01
“Rigorous analytical testing, including techniques like High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and spectroscopy, is employed to verify the purity and identity of the compound.”