For professionals in the chemical and pharmaceutical industries, a deep understanding of the synthesis and specifications of key intermediates like Methyl 4-Fluoro-2-hydroxybenzoate (CAS: 392-04-1) is fundamental. As a crucial compound for drug discovery and organic synthesis, knowing its production route and quality parameters helps in making informed purchasing decisions and ensuring research integrity. When procurement managers search for this product, they often look for 'synthesis of methyl 4-fluoro-2-hydroxybenzoate' and 'methyl 4-fluoro-2-hydroxybenzoate specifications'.

The most common method for synthesizing Methyl 4-Fluoro-2-hydroxybenzoate involves the esterification of 4-fluoro-2-hydroxybenzoic acid. This reaction typically uses methanol as the solvent and esterifying agent, with a strong acid catalyst such as concentrated sulfuric acid. The process involves heating the reactants under reflux conditions for several hours, followed by purification steps like extraction and concentration to isolate the desired product. Manufacturers committed to quality will ensure efficient purification to achieve high yields and purity levels, often exceeding 98%.

Key specifications that buyers look for include not only the purity (e.g., 98% or higher) but also physical properties such as melting point, boiling point, density, and appearance. Methyl 4-Fluoro-2-hydroxybenzoate is typically described as an off-white to light yellow or brown crystalline solid, with a melting point in the range of 38-40 °C. Understanding these parameters helps in assessing the quality and suitability of the material for specific reactions. Suppliers provide this information readily, alongside safety data sheets (SDS) which detail hazard statements and precautionary measures.

When seeking to buy this intermediate, it is essential to partner with manufacturers who can provide consistent quality and reliable supply. Factors like batch-to-batch consistency, proper storage conditions (sealed and dry at room temperature), and transparent communication are hallmarks of a dependable supplier. Many companies actively seek Chinese manufacturers for cost-effective procurement without compromising on quality.

Whether you are a research scientist or a procurement specialist, inquiring about the synthesis process and detailed specifications from potential suppliers is a best practice. This diligence ensures you receive a product that meets your exact needs, whether for laboratory-scale research or larger manufacturing batches. We, as a leading manufacturer and supplier, are committed to providing detailed information and high-quality Methyl 4-Fluoro-2-hydroxybenzoate to support your chemical synthesis endeavors.