Exploring the Synthesis and Uses of N-Benzyloxycarbonyl-L-tyrosine Methyl Ester
N-Benzyloxycarbonyl-L-tyrosine methyl ester (CAS 13512-31-7) is a specialized chemical compound that plays an instrumental role in various sophisticated synthesis processes. As a derivative of the amino acid tyrosine, it is particularly valued in the pharmaceutical and fine chemical sectors for its utility as a protected building block. This article explores its synthesis and diverse applications, offering insights for industry professionals looking to procure this essential material.
The synthesis of N-Benzyloxycarbonyl-L-tyrosine methyl ester typically begins with L-tyrosine methyl ester hydrochloride. The crucial step involves the introduction of the benzyloxycarbonyl (Cbz) protecting group onto the amine function. This is commonly achieved through a reaction with benzyl chloroformate (Z-Cl) in the presence of a base, such as sodium carbonate, under carefully controlled pH conditions. The process requires precise monitoring to ensure efficient protection and minimize side reactions. After the reaction, purification steps, which may include acidification, extraction, washing, drying, and crystallization, are employed to isolate the high-purity product, often yielding a white to off-white solid with a purity exceeding 98.0%. This careful synthesis pathway underscores why it is important to buy from manufacturers who have mastered these techniques.
The applications of N-Benzyloxycarbonyl-L-tyrosine methyl ester are primarily centered around its role as an intermediate. In peptide synthesis, it allows for the selective incorporation of tyrosine residues into peptide chains, leveraging the Cbz group's stability during coupling and its selective removal via hydrogenation. This makes it invaluable for creating complex therapeutic peptides and research peptides. Beyond peptides, this compound is a versatile starting material for the synthesis of various complex organic molecules, including chiral drugs, ligands, and specialty chemicals. Researchers often seek 'how to buy N-Benzyloxycarbonyl-L-tyrosine methyl ester' or 'CAS 13512-31-7 applications' to understand its full potential in their projects.
For industries requiring this compound, sourcing from a reputable manufacturer is key to ensuring quality and supply chain integrity. As a dedicated supplier of fine chemicals, we specialize in producing N-Benzyloxycarbonyl-L-tyrosine methyl ester with the high purity that critical applications demand. Our manufacturing capabilities, coupled with a commitment to stringent quality control, ensure that we can meet the needs of both research laboratories and large-scale production facilities. If you are looking to purchase this compound, we offer competitive pricing and reliable delivery. Contact us to request a quote and discuss your specific requirements for this important chemical intermediate, ensuring your synthesis projects proceed with the highest quality materials.
Perspectives & Insights
Silicon Analyst 88
“After the reaction, purification steps, which may include acidification, extraction, washing, drying, and crystallization, are employed to isolate the high-purity product, often yielding a white to off-white solid with a purity exceeding 98.”
Quantum Seeker Pro
“This careful synthesis pathway underscores why it is important to buy from manufacturers who have mastered these techniques.”
Bio Reader 7
“The applications of N-Benzyloxycarbonyl-L-tyrosine methyl ester are primarily centered around its role as an intermediate.”