In the realm of organic chemistry, the ability to efficiently synthesize and utilize key building blocks is fundamental to innovation. Mesitylacetonitrile (CAS 34688-71-6) stands out as a versatile intermediate, playing a significant role in the development of pharmaceuticals and complex organic molecules. This article delves into the synthesis pathways and the wide-ranging applications of this important chemical compound.

Chemical Profile of Mesitylacetonitrile

Mesitylacetonitrile, with the CAS number 34688-71-6, is a derivative of acetonitrile. Its structure features an acetonitrile group attached to a mesityl (2,4,6-trimethylphenyl) ring. This unique combination of functionalities grants it specific reactivity profiles that are highly valued in synthetic chemistry. The compound's molecular formula is C11H13N, and it has a molecular weight of approximately 159.23 g/mol. It typically presents as a crystalline solid, with purity levels often exceeding 98% when sourced from reputable chemical suppliers.

Synthetic Routes to Mesitylacetonitrile

While the specific industrial synthesis methods can vary among manufacturers, common approaches to preparing Mesitylacetonitrile often involve reactions that introduce the nitrile group onto a mesityl-substituted precursor. For instance, reactions involving halogenated mesityl compounds with cyanide sources are typical. The precise methods are often proprietary to chemical manufacturers, who optimize these processes for yield, purity, and cost-effectiveness to supply the market with consistent quality material.

Applications in Pharmaceutical and Chemical Industries

The primary utility of Mesitylacetonitrile lies in its role as an intermediate in the synthesis of more complex chemical structures. In the pharmaceutical sector, it has been employed in the development of novel drug candidates. For example, it has been used in synthetic routes for compounds targeting stress-related disorders and has shown potential in the creation of anti-HIV agents. Beyond pharmaceuticals, Mesitylacetonitrile is a valuable building block in general organic synthesis, enabling chemists to construct a variety of organic molecules with specific functional groups and architectures. Researchers frequently buy this compound for R&D purposes, exploring its reactivity in various chemical transformations.

Sourcing Mesitylacetonitrile

For companies looking to procure Mesitylacetonitrile, partnering with reliable chemical suppliers and manufacturers is essential. These suppliers provide the necessary quality assurance, including Certificates of Analysis (CoA), and ensure a steady supply to meet production demands. Whether you are a research scientist needing small quantities for laboratory experiments or a procurement manager sourcing bulk materials for industrial production, understanding the availability and pricing from various manufacturers in regions like China can help in making informed purchasing decisions. Engaging with a trusted chemical supplier is key to obtaining high-purity Mesitylacetonitrile for your synthesis needs.