Tankyrase Inhibition: Exploring XAV939's Mechanism and Sourcing Options
Tankyrase enzymes (TNKS1 and TNKS2) are key regulators within the Wnt signaling pathway, playing critical roles in cellular processes such as proliferation, differentiation, and stemness. Inhibiting these enzymes offers a promising therapeutic strategy, particularly in oncology and regenerative medicine. XAV939, with its CAS number 284028-89-3, is a well-characterized and potent inhibitor of Tankyrases, making it a compound of significant interest for researchers. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer in China, provides high-quality XAV939 to meet the global demand for this essential research chemical.
The mechanism of XAV939 involves binding to the NAD+ binding site of Tankyrase enzymes, thereby inhibiting their PARP activity. This inhibition leads to the stabilization of Axin proteins, which are part of the β-catenin destruction complex. Consequently, XAV939 effectively suppresses the canonical Wnt signaling pathway. Researchers looking to buy XAV939 for their studies can be assured of its efficacy in modulating Wnt signaling. NINGBO INNO PHARMCHEM ensures that our XAV939 product maintains a minimum purity of 98%, which is crucial for obtaining reliable and reproducible experimental data in biochemical assays and cellular studies.
As a primary manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. focuses on providing competitive XAV939 price points without compromising on quality. We understand the logistical challenges faced by researchers worldwide and have established a robust supply chain to ensure prompt and safe delivery of our products. If you are seeking to order XAV939, our experienced team is ready to assist you with obtaining a quotation and processing your purchase efficiently. We are committed to being your trusted source for critical research intermediates.
The scientific community's interest in Tankyrase inhibition and its therapeutic potential continues to grow. By supplying high-purity XAV939, NINGBO INNO PHARMCHEM aims to support these vital research efforts. We encourage scientists and procurement managers to contact us to discuss their specific requirements for XAV939 and to explore how our reliable supply and quality assurance can benefit their research projects. Partner with us for your chemical sourcing needs and contribute to the advancement of scientific knowledge.
Perspectives & Insights
Agile Reader One
“We understand the logistical challenges faced by researchers worldwide and have established a robust supply chain to ensure prompt and safe delivery of our products.”
Logic Vision Labs
“If you are seeking to order XAV939, our experienced team is ready to assist you with obtaining a quotation and processing your purchase efficiently.”
Molecule Origin 88
“We are committed to being your trusted source for critical research intermediates.”