For chemists, R&D scientists, and procurement specialists, a thorough understanding of a chemical intermediate's properties and safe handling procedures is non-negotiable. 2-Ethylhexanoyl Chloride (CAS 760-67-8) is a reactive acyl chloride that demands precise knowledge for its effective and safe utilization. As a leading manufacturer and supplier of fine chemicals, we provide this technical insight to empower our clients. This deep dive focuses on the physical and chemical characteristics, safety considerations, and common applications of this vital compound.

Physical and Chemical Properties

Appearance: 2-Ethylhexanoyl Chloride is typically described as a clear, colorless to greyish liquid. Its visual clarity is an important initial indicator of its purity.
CAS Number: 760-67-8 is its definitive identifier in chemical databases and regulatory documents.
Molecular Formula: C8H15ClO. This formula reveals its composition: an eight-carbon chain with a carbonyl chloride functional group.
Molecular Weight: Approximately 162.66 g/mol. This is a key parameter for stoichiometric calculations in synthesis.
Reactivity: As an acyl chloride, it is highly reactive, particularly with nucleophiles. It readily undergoes hydrolysis in the presence of water, producing hydrochloric acid and 2-ethylhexanoic acid. This characteristic necessitates careful handling and storage in anhydrous conditions.
Solubility: It is miscible with most common organic solvents, which is advantageous for its use in various reaction media. However, its reactivity with protic solvents like water and alcohols must be considered.

Key Applications and Use Cases

The properties of 2-Ethylhexanoyl Chloride make it invaluable across several industries:

  • Organic Synthesis: Its acyl chloride functionality makes it an excellent acylating agent. It's used to introduce the 2-ethylhexanoyl group into other organic molecules, a common step in the synthesis of complex compounds.
  • Pharmaceutical Intermediates: In the pharmaceutical sector, it serves as a critical building block for synthesizing APIs and complex drug structures. Its purity and reactivity are essential for efficient drug synthesis pathways.
  • Cosmetic Ingredients: It can be employed in specialized cosmetic formulations, contributing to specific properties of the final product.
  • Organic Peroxide Production: A significant industrial use is in the manufacturing of organic peroxides, which are vital as polymerization initiators.

Safety and Handling Considerations

Given its reactivity and potential to release corrosive hydrochloric acid upon contact with moisture, proper safety protocols are imperative:

  • Personal Protective Equipment (PPE): Always wear chemical-resistant gloves (e.g., nitrile, neoprene), safety goggles or a face shield, and protective clothing.
  • Ventilation: Handle in a well-ventilated area, preferably under a fume hood, to prevent inhalation of vapors.
  • Storage: Store in tightly sealed containers in a cool, dry, and well-ventilated place, away from incompatible materials such as water, strong bases, alcohols, and oxidizing agents. Anhydrous conditions are crucial.
  • Spill Response: In case of spills, contain the material and neutralize with a suitable absorbent, then dispose of according to local regulations.

Sourcing High-Quality 2-Ethylhexanoyl Chloride

For procurement professionals, sourcing 2-Ethylhexanoyl Chloride (CAS 760-67-8) from a reputable manufacturer ensures both quality and safety compliance. Our China-based manufacturing facility is equipped to produce this compound with high purity and provides comprehensive safety data sheets (SDS) for proper handling. We encourage you to contact us for a quote and to discuss your specific technical requirements, ensuring you procure a product that meets all necessary specifications for your applications.

Conclusion

2-Ethylhexanoyl Chloride is a powerful chemical tool, but its effective use hinges on understanding its technical characteristics and safety protocols. By providing detailed information on its properties and offering high-purity material from our advanced manufacturing facility, we empower our clients to leverage this intermediate with confidence. Reach out to us to secure your supply of quality 2-Ethylhexanoyl Chloride.