For researchers and development scientists in the pharmaceutical and chemical industries, a thorough understanding of the technical specifications of key intermediates is crucial for successful project outcomes. Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate (CAS: 141942-85-0) is one such critical compound, widely utilized as a chiral building block in complex organic synthesis, particularly for statin drugs. As a prominent manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of these specifications.

Key Physicochemical Properties

When you buy Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, these technical details are vital for its effective application:

  • Appearance: Typically a colorless to pale yellow viscous liquid. This visual characteristic is an initial indicator of product quality.
  • Purity (HPLC/GC): Guaranteed purity of 97%min, often exceeding 98% or 99% for critical applications, ensures minimal interference from impurities in synthesis.
  • Molecular Formula & Weight: C7H11NO3, with a molecular weight of 157.17 g/mol, providing essential data for stoichiometric calculations.
  • CAS Number: 141942-85-0 – the definitive identifier for this chemical entity.
  • Optical Rotation: The characteristic optical rotation, such as [α]D20 = -12.5° to -14.5° (c=1, MeOH), confirms the desired (R)-chirality.
  • Boiling Point: Approximately 285°C (with decomposition), indicating thermal stability under certain conditions.
  • Solubility: Miscible with common organic solvents like ethanol, acetone, and DMSO, but immiscible with water, guiding formulation and reaction solvent choices.

Applications and Quality Assurance

These specifications are critical for its role as a precursor in synthesizing APIs like Atorvastatin and Rosuvastatin. Researchers depend on the consistent quality and accurate specifications of this intermediate for reliable experimental results and scalable manufacturing processes. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive Certificates of Analysis (CoA) with each batch, detailing all relevant technical data, including chiral purity verification. If you are in R&D and need to purchase this vital intermediate, our commitment to quality ensures you receive a product that meets your exacting standards.