Teriflunomide CAS 108605-62-5: Chemical Synthesis and Research Applications
Teriflunomide, scientifically known as (Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide and identified by CAS number 108605-62-5, is a significant molecule within the fine chemical and pharmaceutical sectors. As a potent inhibitor of dihydroorotate dehydrogenase (DHODH), it plays a crucial role in pyrimidine synthesis, a pathway essential for rapidly dividing cells. This characteristic underpins its utility in research and its development as a therapeutic agent. For those in the chemical synthesis and pharmaceutical industries, understanding the nuances of Teriflunomide is key to its effective procurement and application.
The chemical synthesis of Teriflunomide involves intricate organic chemistry processes, ensuring the final product meets stringent purity and structural integrity standards. When sourcing this compound, researchers and formulators typically look for suppliers who can provide detailed specifications, including its molecular formula (C12H9F3N2O2), molecular weight (270.21 g/mol), and solubility data. Teriflunomide is generally insoluble in water but demonstrates good solubility in DMSO, a common solvent in biological assays and chemical reactions. Availability of a reliable Teriflunomide manufacturer is crucial for consistent product quality.
In terms of research applications, Teriflunomide is primarily investigated for its immunomodulatory and antiproliferative effects. Its ability to inhibit lymphoid cell proliferation and its active metabolite status from leflunomide make it a subject of interest in autoimmune disease research, particularly for conditions like multiple sclerosis. Scientists looking to purchase Teriflunomide for in vitro or in vivo studies will often search for terms like 'Teriflunomide supplier China' or 'buy Teriflunomide for research.' The price of Teriflunomide can vary based on quantity and purity, making it important to request quotes from multiple suppliers to secure the best value.
For procurement managers, identifying a trusted manufacturer that offers Teriflunomide at a competitive price is a strategic objective. A reliable supplier not only provides high-quality chemical intermediates but also ensures timely delivery and responsive customer service. Whether you are a large pharmaceutical company or a specialized research institution, securing a consistent supply chain for essential compounds like Teriflunomide is paramount. Consider partnering with a manufacturer that can handle bulk orders and offers technical support for your synthesis and formulation needs.
In summary, Teriflunomide (CAS 108605-62-5) is a valuable pharmaceutical intermediate with diverse research applications. By understanding its chemical properties, biological activity, and the importance of sourcing from reputable manufacturers, your organization can ensure the successful implementation of your research and development projects. We are a leading supplier of Teriflunomide in China, dedicated to providing high-quality products and exceptional service.
Perspectives & Insights
Silicon Analyst 88
“This characteristic underpins its utility in research and its development as a therapeutic agent.”
Quantum Seeker Pro
“For those in the chemical synthesis and pharmaceutical industries, understanding the nuances of Teriflunomide is key to its effective procurement and application.”
Bio Reader 7
“The chemical synthesis of Teriflunomide involves intricate organic chemistry processes, ensuring the final product meets stringent purity and structural integrity standards.”