The global pharmaceutical industry relies heavily on a consistent supply of high-quality chemical intermediates to drive drug discovery and development. tert-Butyl 3-Methanesulfonyloxymethyl-pyrrolidine-1-carboxylate, identified by CAS number 141699-56-1, is one such vital compound. Its unique chemical structure and reactivity make it an indispensable building block for synthesizing a wide range of complex molecules, particularly those with therapeutic applications. For chemical manufacturers, distributors, and R&D professionals, understanding the sourcing and technical aspects of this intermediate is crucial for efficient operations and successful project outcomes.

Chemical Profile and Significance

tert-Butyl 3-Methanesulfonyloxymethyl-pyrrolidine-1-carboxylate is characterized by its pyrrolidine ring system, protected by a tert-butoxycarbonyl (Boc) group, and featuring a methanesulfonyloxy (mesylate) group attached via a methylene linker. This combination of functional groups imparts significant synthetic utility. The Boc group can be easily cleaved under acidic conditions, revealing the secondary amine for further reactions, such as amide formation or alkylation. The mesylate group is a well-known leaving group, readily undergoing nucleophilic substitution reactions, allowing for the introduction of various nucleophiles at this position. This makes the compound an excellent starting material for creating novel pyrrolidine-containing scaffolds, which are common in many pharmaceutical agents. Procurement managers often look for this specific 'pharmaceutical intermediate' when planning their synthesis campaigns.

Supplier Landscape and Quality Assurance

The global market for pharmaceutical intermediates is competitive, with many suppliers offering a wide range of products. When seeking to 'buy' tert-Butyl 3-Methanesulfonyloxymethyl-pyrrolidine-1-carboxylate, it is imperative to partner with a reliable 'manufacturer' or 'supplier,' often sought through terms like 'CAS 141699-56-1 supplier China.' Quality assurance is paramount; buyers need to verify that suppliers can provide detailed specifications, including purity levels (e.g., >97% or >98%), and a comprehensive Certificate of Analysis (CoA). Furthermore, understanding the supplier's production capacity, lead times, and adherence to international quality standards ensures a dependable supply for ongoing projects.

Applications in Drug Development and Research

The primary application of tert-Butyl 3-Methanesulfonyloxymethyl-pyrrolidine-1-carboxylate lies in its role as a versatile intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its functionalized pyrrolidine core can be incorporated into molecules targeting various diseases. Beyond pharmaceutical applications, it also finds use in academic and industrial research for exploring new synthetic methodologies and developing novel organic compounds. For researchers, knowing the 'price' and availability from trusted 'suppliers' is critical for budgeting and experimental planning. Companies interested in custom synthesis of related compounds may also find manufacturers offering such services.