For researchers and formulation chemists, identifying versatile and reliable chemical building blocks is essential for innovation. Tert-butyl 5-oxo-L-prolinate (CAS 35418-16-7), a chiral organic compound presented as a white powder, stands out due to its significant utility in specialized synthesis. Its structural features make it a valuable precursor, particularly in the complex synthesis of natural products and advanced imaging agents.

As a starting material, Tert-butyl 5-oxo-L-prolinate plays a pivotal role in the synthesis of phenanthroindolizidine alkaloids. Compounds like (+)-tylophorine and antofine, which have demonstrated promising anti-cancer and anti-inflammatory activities, rely on this intermediate for their intricate molecular frameworks. Procurement managers seeking these specialized compounds will find that securing a consistent supply of high-quality Tert-butyl 5-oxo-L-prolinate is a fundamental requirement.

Beyond natural product chemistry, Tert-butyl 5-oxo-L-prolinate is also instrumental in the development of radioligands. It serves as a key starting material for synthesizing radioligands such as [18F]IUR-1602 and [18F]IUR-1601. These are crucial for imaging of P2X7R, a therapeutic target relevant to neuroinflammation. The demand for such advanced precursors underscores the importance of sourcing from reputable manufacturers who can guarantee purity and precise specifications.

For procurement professionals looking to buy Tert-butyl 5-oxo-L-prolinate, understanding its chemical properties, such as its melting point range (102.0-108.0 °C) and solubility, is important. Working with a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures that you receive a product that meets industry standards, facilitating smoother research and development processes. We are committed to being a premier supplier, offering this essential intermediate at competitive prices for both research quantities and bulk orders.

In summary, Tert-butyl 5-oxo-L-prolinate (CAS 35418-16-7) is a highly valuable intermediate with critical applications in alkaloid synthesis and radioligand development. By choosing a reliable manufacturer and supplier, pharmaceutical companies can ensure the quality and availability needed for their cutting-edge research. Contact us today to learn more about our product offerings and how we can support your synthetic chemistry needs.