Tert-Butyl Mesylate, identified by CAS number 16427-41-1, is a chemical compound that plays a significant role as an intermediate in the synthesis of pharmaceuticals and various fine chemicals. For researchers and industrial chemists, understanding its properties and applications is key to optimizing synthetic pathways and ensuring product quality. This article delves into the importance of Tert-Butyl Mesylate as a raw material for specialized chemical production.

With a molecular formula of C5H12O3S and a molecular weight of 152.21 g/mol, Tert-Butyl Mesylate is a liquid compound often characterized by its high purity, typically exceeding 97%. Its utility stems from its chemical structure, which makes it an effective methylsulfonating agent. This characteristic is particularly valuable in organic synthesis, where the introduction of specific functional groups is critical for building complex molecules.

Pharmaceutical Synthesis Applications

In the pharmaceutical industry, Tert-Butyl Mesylate serves as a crucial intermediate. It is frequently employed in the synthesis of Active Pharmaceutical Ingredients (APIs). The ability to precisely introduce a tert-butyl mesylate group can facilitate subsequent reactions, enabling the creation of more complex drug molecules. Pharmaceutical manufacturers seeking reliable sources for this compound often look for suppliers that can guarantee consistent purity and batch-to-batch uniformity, understanding that these factors directly impact the efficacy and safety of the final drug product.

When considering purchasing Tert-Butyl Mesylate for pharmaceutical applications, it's important to work with manufacturers who adhere to strict quality control measures. This ensures that the intermediate meets the rigorous standards required for drug development and production. Enquiring about the supplier's manufacturing capabilities and quality assurance protocols is a standard step for any R&D scientist or procurement manager.

Role in Fine Chemical Production

Beyond pharmaceuticals, Tert-Butyl Mesylate is also indispensable in the broader field of fine chemicals. It acts as a versatile building block for creating specialized chemicals used in diverse industries, including agrochemicals, materials science, and specialty polymers. Its reactivity allows chemists to tailor molecular structures to achieve desired properties, making it a valuable component in custom synthesis projects.

Companies that manufacture or supply Tert-Butyl Mesylate often highlight its role in enabling advanced chemical transformations. For instance, it can be used in esterification reactions or as a protecting group precursor, demonstrating its flexibility in synthetic strategies. The demand for such intermediates underscores the importance of a robust chemical supply chain, where manufacturers can be counted on for consistent product availability and competitive pricing.

Sourcing and Procurement Advice

For businesses looking to source Tert-Butyl Mesylate, particularly from manufacturers in China, it is advisable to conduct thorough due diligence. Identifying suppliers who can provide detailed product specifications, safety data sheets, and responsive customer service is key. Engaging with manufacturers for quotations ensures that you are obtaining the best possible price for this critical chemical intermediate. Whether for large-scale industrial production or specialized research, Tert-Butyl Mesylate remains a valuable chemical asset.