For research and development scientists and formulation chemists in the pharmaceutical industry, the selection of high-quality chemical building blocks is fundamental to innovation. Tert-Butyl Thiazol-4-ylcarbamate, identified by CAS number 1235406-42-4, stands out as a particularly valuable intermediate due to its versatile chemical structure and proven utility in synthesizing complex pharmaceutical compounds. Understanding its properties and applications can significantly enhance your R&D efforts.

Tert-Butyl Thiazol-4-ylcarbamate, also recognized as 4-(Boc-amino)thiazole, is characterized by its molecular formula C8H12N2O2S and a molar mass of approximately 200.26 g/mol. As a solid with a melting point of 153-155 °C, it offers good handling stability. The presence of the tert-butoxycarbonyl (Boc) protecting group on the amine function of the thiazole ring is key to its synthetic utility. This protecting group can be selectively removed under specific conditions, allowing chemists to introduce other functional groups or extend molecular chains with precision. This selectivity is vital when constructing intricate molecular architectures commonly found in modern pharmaceuticals.

The primary application of Tert-Butyl Thiazol-4-ylcarbamate lies in pharmaceutical synthesis. It serves as a critical starting material or intermediate for the development of novel Active Pharmaceutical Ingredients (APIs). Its thiazole core is a common pharmacophore found in a range of therapeutic agents, including antibacterials, antifungals, and anti-inflammatory drugs. By using this pre-functionalized intermediate, researchers can streamline synthesis routes, reduce reaction steps, and improve overall yields. This makes it an attractive component for drug discovery programs aiming to rapidly screen and optimize potential drug candidates.

Beyond its role in API synthesis, Tert-Butyl Thiazol-4-ylcarbamate is also a valuable reagent in general organic chemistry. Its reactive sites can be leveraged in various coupling reactions, cyclizations, and functional group transformations. Scientists developing new synthetic methodologies may find this compound a useful model substrate for testing innovative chemical processes. The availability of high-purity material from reputable manufacturers ensures reproducibility in experimental outcomes, a cornerstone of scientific research.

When sourcing Tert-Butyl Thiazol-4-ylcarbamate for your research needs, it is important to engage with reliable suppliers. Manufacturers offering material with a purity of 97% min or higher, along with comprehensive technical data sheets and safety information, are preferred. The ability to purchase in research-appropriate quantities, such as grams or tens of grams, is essential for laboratory-scale work. As projects scale up, having a supplier who can also provide larger quantities (kilograms or bulk) is a significant advantage, ensuring continuity from discovery to development.

In conclusion, Tert-Butyl Thiazol-4-ylcarbamate (CAS 1235406-42-4) is an indispensable chemical intermediate for pharmaceutical R&D scientists and formulation chemists. Its unique structure, high purity, and established applications in organic synthesis make it a cornerstone for developing next-generation therapeutics. By choosing a trusted supplier, you can ensure access to this critical building block, accelerating your path to scientific breakthroughs.