In the intricate landscape of organic synthesis, reagents that enable specific and efficient chemical transformations are highly prized. Tetrabenzyl Pyrophosphate, identifiable by its CAS number 990-91-0, stands out as a powerful and versatile phosphorylating agent, finding broad utility in both academic research and industrial applications, particularly within the pharmaceutical sector. For B2B clients, understanding its capabilities is key to leveraging its potential in their synthetic endeavors.

Tetrabenzyl Pyrophosphate (CAS 990-91-0) is an organophosphorus compound with the molecular formula C28H28O7P2 and a molecular weight of 538.47. It is typically supplied as a white crystalline powder, making it convenient for handling and precise measurement in synthetic procedures. Its defining characteristic is its ability to efficiently transfer phosphate groups, a process known as phosphorylation. This capability makes it an indispensable tool for chemists aiming to modify organic molecules by introducing phosphoryl moieties.

The versatility of Tetrabenzyl Pyrophosphate as a phosphorylating agent is demonstrated through its diverse applications:

  • Synthesis of Phosphorylated Compounds: It is widely used for the synthesis of various phosphorylated organic molecules. This includes phosphorylating alcohols, amines, and even more complex substrates like nucleosides and nucleotides. These phosphorylated derivatives often exhibit altered biological activities, improved water solubility, or serve as prodrugs, making them valuable in pharmaceutical development.
  • Pharmaceutical Intermediate: As mentioned previously, Tetrabenzyl Pyrophosphate is a critical intermediate in the synthesis of certain pharmaceuticals, most notably antiemetic drugs. Its structured reactivity allows for controlled introduction of phosphate groups, essential for creating the specific molecular architecture required for therapeutic action. Researchers looking to buy this compound for drug discovery are leveraging its established utility.
  • Preparation of Specific Derivatives: It plays a role in the preparation of specific organophosphorus compounds, such as dibenzyl phosphoro fluoridate, under catalytic conditions. This highlights its utility in creating specialized reagents for further synthetic manipulation.
  • Research in Materials Science and Analytical Chemistry: Beyond medicinal chemistry, its properties have been explored in the development of ion-selective membranes, indicating potential applications in analytical chemistry and materials science where precise ion recognition is required.

For B2B clients, sourcing Tetrabenzyl Pyrophosphate from reliable manufacturers and suppliers is crucial for ensuring consistent results. The effectiveness of this reagent is directly tied to its purity. High-purity Tetrabenzyl Pyrophosphate (often ≥99% by HPLC) minimizes the risk of unwanted side reactions and ensures predictable outcomes in complex synthetic pathways. When considering price, buyers should look for a balance between cost-effectiveness and guaranteed quality, as low-purity reagents can lead to costly process failures.

The global chemical market offers numerous options for sourcing Tetrabenzyl Pyrophosphate. Manufacturers in China are prominent suppliers, often providing competitive wholesale price points due to their advanced production capabilities and economies of scale. When evaluating potential suppliers, it is important to consider their technical support, adherence to quality standards, and their ability to provide comprehensive documentation such as Certificates of Analysis (COA). Establishing a relationship with a trusted supplier ensures a stable and reliable source for this essential synthetic tool.

In conclusion, Tetrabenzyl Pyrophosphate (CAS 990-91-0) is a cornerstone reagent for organic synthesis, offering significant versatility as a phosphorylating agent. Its applications span from fundamental research to the critical production of pharmaceuticals. By understanding its properties and engaging with reputable suppliers, B2B purchasers can effectively utilize this powerful compound to drive innovation and achieve their synthetic objectives.