The Science Behind Tetramisole Hydrochloride (CAS 5086-74-8) as an Alkaline Phosphatase Inhibitor
Tetramisole Hydrochloride, bearing the CAS number 5086-74-8, is more than just an anthelmintic; it is a significant tool in biochemical research, particularly for its potent ability to inhibit alkaline phosphatases. This characteristic makes it invaluable for scientists studying enzyme kinetics, cellular signaling pathways, and various physiological processes where alkaline phosphatase activity plays a critical role.
Alkaline phosphatases are a group of enzymes found in numerous tissues throughout the body, including the liver, bone, intestines, and placenta. They are involved in a wide range of biological functions, such as bone mineralization, lipid absorption, and cellular metabolism. By selectively inhibiting these enzymes, Tetramisole Hydrochloride allows researchers to elucidate their specific roles without interfering with other cellular processes. Understanding the Tetramisole hydrochloride mechanism of action as an inhibitor is key to designing effective experimental protocols.
The efficacy of Tetramisole Hydrochloride as an alkaline phosphatase inhibitor is well-documented, with studies indicating its effectiveness in the range of 0.4–2 mM. While intestinal alkaline phosphatases show only slight inhibition, other isoforms are significantly affected. This specific inhibitory profile makes Tetramisole HCl a preferred reagent for many in vitro experiments. For researchers, ensuring the Tetramisole hydrochloride purity and assay of the compound is critical to obtain reproducible and reliable results.
Sourcing high-quality Tetramisole Hydrochloride from reputable Tetramisole hydrochloride suppliers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., is crucial for research integrity. These suppliers provide compounds that meet stringent specifications, ensuring consistent performance in laboratory settings. Adhering to proper Tetramisole hydrochloride storage conditions is also vital to maintain its inhibitory capacity over time.
In conclusion, Tetramisole Hydrochloride (CAS 5086-74-8) serves a dual purpose: a vital anthelmintic and a powerful biochemical research tool. Its capacity to inhibit alkaline phosphatases opens avenues for significant scientific discovery. By relying on expert Tetramisole hydrochloride manufacturers in China for quality and consistency, researchers can confidently advance their studies in cellular biology and enzymology.
Perspectives & Insights
Nano Explorer 01
“Alkaline phosphatases are a group of enzymes found in numerous tissues throughout the body, including the liver, bone, intestines, and placenta.”
Data Catalyst One
“They are involved in a wide range of biological functions, such as bone mineralization, lipid absorption, and cellular metabolism.”
Chem Thinker Labs
“By selectively inhibiting these enzymes, Tetramisole Hydrochloride allows researchers to elucidate their specific roles without interfering with other cellular processes.”